EMT in cervical cancer: its role in tumour progression and response to therapy

R Qureshi, H Arora, MA Rizvi - Cancer letters, 2015 - Elsevier
The prognosis of cervical patients significantly decreases as the cancer metastasizes to
other parts of the body. The epithelial to mesenchymal transition (EMT) plays an important …

Molecular landscape of recurrent cervical cancer

D Adiga, S Eswaran, D Pandey, K Sharan… - Critical Reviews in …, 2021 - Elsevier
Cervical cancer (CC) is a major gynecological problem in developing and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …

[HTML][HTML] Keratin 17 in premalignant and malignant squamous lesions of the cervix: proteomic discovery and immunohistochemical validation as a diagnostic and …

LF Escobar-Hoyos, J Yang, J Zhu, JA Cavallo, H Zhai… - Modern Pathology, 2014 - Elsevier
Most previously described immunohistochemical markers of cervical high-grade squamous
intraepithelial lesion (HSIL) and squamous cell carcinoma may help to improve diagnostic …

Versatility of RNA‐binding proteins in cancer

L Wurth - International Journal of Genomics, 2012 - Wiley Online Library
Posttranscriptional gene regulation is a rapid and efficient process to adjust the proteome of
a cell to a changing environment. RNA‐binding proteins (RBPs) are the master regulators of …

Increased RIPK4 expression is associated with progression and poor prognosis in cervical squamous cell carcinoma patients

DQ Liu, FF Li, JB Zhang, TJ Zhou, WQ Xue… - Scientific reports, 2015 - nature.com
Aberrant expression of receptor interacting protein kinase 4 (RIPK4), a crucial regulatory
protein of Wnt/β-catenin signaling, has recently been reported to be involved in several …

The role of RNA splicing factors in cancer: regulation of viral and human gene expression in human papillomavirus-related cervical cancer

A Cerasuolo, L Buonaguro, FM Buonaguro… - Frontiers in cell and …, 2020 - frontiersin.org
The spliceosomal complex components, together with the heterogeneous nuclear
ribonucleoproteins (hnRNPs) and serine/arginine-rich (SR) proteins, regulate the process of …

SAM68: signal transduction and RNA metabolism in human cancer

P Frisone, D Pradella, A Di Matteo… - BioMed Research …, 2015 - Wiley Online Library
Alterations in expression and/or activity of splicing factors as well as mutations in cis‐acting
splicing regulatory sequences contribute to cancer phenotypes. Genome‐wide studies have …

RNA-binding proteins: Underestimated contributors in tumorigenesis

Y Zhao, C Mir, Y Garcia-Mayea, R Paciucci… - Seminars in Cancer …, 2022 - Elsevier
Abstract mRNA export, translation, splicing, cleavage or capping determine mRNA stability,
which represents one of the primary aspects regulating gene expression and function. RNA …

High expression of FUNDC1 predicts poor prognostic outcomes and is a promising target to improve chemoradiotherapy effects in patients with cervical cancer

H Hou, P Er, J Cheng, X Chen, X Ding… - Cancer …, 2017 - Wiley Online Library
Abstract FUN14 domain containing 1 (FUNDC1) is an important molecule in receptor‐
dependent mitophagy. However, the roles of FUNDC1 in human cancer biology remain …

Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial–mesenchymal transition and activation of Akt/GSK-3β/Snail …

J Zhang, J Wei, J Lu, Z Tong, B Liao, B Yu… - …, 2013 - academic.oup.com
Rab25, an epithelial-specific member of the Rab family of small guanosine triphosphatases,
is associated with several human cancers. The goal of this study was to determine its …