RNAs are involved in the crucial processes of disease progression and have emerged as
powerful therapeutic targets and diagnostic biomarkers. However, efficient delivery of …

The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …

DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …

The specific bonding of DNA base pairs provides the chemical foundation for genetics. This
powerful molecular recognition system can be used in nanotechnology to direct the …

Like DNA, RNA can be designed and manipulated to produce a variety of different
nanostructures. Moreover, RNA has a flexible structure and possesses catalytic functions …

In biology, nucleic acids are carriers of molecular information: DNA's base sequence stores
and imparts genetic instructions, while RNA's sequence plays the role of a messenger and a …

Human civilization has witnessed the use of materials-derived from biomolecules of plants
and animal origin for biomedical applications since ancient era. In recent years, precision …

Paclitaxel is widely used in cancer treatments, but poor water-solubility and toxicity raise
serious concerns. Here we report an RNA four-way junction nanoparticle with ultra …

Triple-negative breast cancer (TNBC) is an aggressive disease with a short median time
from relapse to death. The increased aggressiveness, drug resistance, disease relapse, and …

Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …