Significance: Social and demographic changes have led to an increased prevalence of
loneliness and social isolation in modern society. Recent Advances: Population-based …

Significance: Severe life stress (SLS), as opposed to trivial everyday stress, is defined as a
serious psychosocial event with the potential of causing an impacting psychological …

Loneliness and social isolation are common sources of chronic stress in modern society.
Epidemiological studies have demonstrated that loneliness and social isolation increase …

Stress is an inevitable part of human life and it is experienced even before birth. Stress to
some extent could be considered normal and even necessary for the survival and the …

Severe socioeconomic deprivation (SED) and adverse childhood experiences (ACE) are
significantly associated with the development in adulthood of (i) enhanced inflammatory …

The effects of C60FAS (50 and 500 μg/kg) supplementation, in a normal physiological state
and after restraint stress exposure, on prooxidant/antioxidant balance in rat tissues were …

Social isolation (SI) rearing of rodents is a developmental manipulation, which is commonly
compared with the psychological stressors in humans as it produces several behavioral …

Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …

The mammalian brain has high energy demands, which may become higher in response to
environmental challenges such as psychogenic stress exposure. Therefore, efficient …

Chronic stress is a contributing risk factor in the development of psychiatric illnesses,
including depressive disorders. The mechanisms of their psychopathology are multifaceted …