Carbon dots as dual inhibitors of tau and amyloid-beta aggregation for the treatment of Alzheimer's disease

W Zhang, N Smith, Y Zhou, CM McGee, M Bartoli, S Fu… - Acta Biomaterialia, 2024 - Elsevier
Alzheimer's disease (AD) is the most common form of senile dementia, presenting a
significant challenge for the development of effective treatments. AD is characterized by …

Unravelling the potential of yolkin for nutraceutical use: the origin, structure, and functional insights of a hen egg yolk polypeptide complex

A Zambrowicz, K Kapczyńska, P Kania, JS Nowak… - Food & Function, 2024 - pubs.rsc.org
Nutraceuticals can reduce the risk of many diseases, such as cardiovascular disease,
immune deficiencies, neurodegeneration, and others. Their delivery remains a challenge …

Cystatins: unravelling the biological implications for neuroprotection

B Stańczykiewicz, M Łuc, M Banach… - Archives of Medical …, 2023 - pmc.ncbi.nlm.nih.gov
Cystatins, a family of proteins known for their inhibitory role against cysteine proteases, have
garnered significant attention in the field of neurodegeneration. Numerous genetic …

Innovative Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging and Its Utility in Whole-Brain Visualization

X Yan, X Chen, Z Shan, L Bi - ACS omega, 2024 - ACS Publications
Conducting in vivo brain imaging can be a challenging task due to the complexity of brain
tissue and the strict requirements for safe and effective imaging agents. However, a new …

Targeting and Imaging Mitochondria with a Novel Cyanine-based Fluorescent Dye and Its Application to Whole Brain Imaging

X Yan, X Chen, Z Shan, L Bi - bioRxiv, 2023 - biorxiv.org
In vivo, brain imaging poses several challenges due to the complexity of brain tissue and the
requirements for effective and safe imaging. In this manuscript, we reported on developing a …