Game Theory for Managing Evolving Systems: Challenges and Opportunities of Including Vector-Valued Strategies and Life-History Traits
Nature exhibits rapid evolution in response to human activities. When using natural
resources for their own profit, humans should account for such responses. Stackelberg …
resources for their own profit, humans should account for such responses. Stackelberg …
Matrix community models for ecology and evolution
Ecological communities are shaped by biotic interactions as well as environmental forces,
and both must be incorporated to obtain models capable of forecasting realistic community …
and both must be incorporated to obtain models capable of forecasting realistic community …
The contribution of evolvability to the eco‐evolutionary dynamics of competing species
Evolvability is the capacity of a population to generate heritable variation that can be acted
upon by natural selection. This ability influences the adaptations and fitness of individual …
upon by natural selection. This ability influences the adaptations and fitness of individual …
A mathematical investigation of polyaneuploid cancer cell memory and cross-resistance in state-structured cancer populations
The polyaneuploid cancer cell (PACC) state promotes cancer lethality by contributing to
survival in extreme conditions and metastasis. Recent experimental evidence suggests that …
survival in extreme conditions and metastasis. Recent experimental evidence suggests that …
Modeling stress-induced responses: plasticity in continuous state space and gradual clonal evolution
A Bukkuri - Theory in Biosciences, 2024 - Springer
Mathematical models of cancer and bacterial evolution have generally stemmed from a
gene-centric framework, assuming clonal evolution via acquisition of resistance-conferring …
gene-centric framework, assuming clonal evolution via acquisition of resistance-conferring …
Eco-evolutionary dynamics of structured populations in periodically fluctuating environments: a G function approach
A Bukkuri - Theory in Biosciences, 2024 - Springer
Understanding the ecological and evolutionary dynamics of populations is critical for both
basic and applied purposes in a variety of biological contexts. Although several modeling …
basic and applied purposes in a variety of biological contexts. Although several modeling …
Cell types or cell states? An investigation of adrenergic and mesenchymal cell phenotypes in neuroblastoma
Neuroblastoma exhibits two cellular phenotypes: therapy-sensitive adrenergic (ADRN) and
therapy-resistant mesenchymal (MES). To understand treatment response, it is important to …
therapy-resistant mesenchymal (MES). To understand treatment response, it is important to …