Targeting cannabinoid receptors: current status and prospects of natural products

D An, S Peigneur, LA Hendrickx, J Tytgat - International journal of …, 2020 - mdpi.com
Cannabinoid receptors (CB1 and CB2), as part of the endocannabinoid system, play a
critical role in numerous human physiological and pathological conditions. Thus …

[HTML][HTML] Cannabinoids in cancer treatment: Therapeutic potential and legislation

B Dariš, MT Verboten, Ž Knez, P Ferk - Bosnian journal of basic …, 2019 - ncbi.nlm.nih.gov
The plant Cannabis sativa L. has been used as an herbal remedy for centuries and is the
most important source of phytocannabinoids. The endocannabinoid system (ECS) consists …

Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

Cannabis and its constituents for cancer: History, biogenesis, chemistry and pharmacological activities

S Lal, A Shekher, AS Narula, H Abrahamse… - Pharmacological …, 2021 - Elsevier
Cannabis has long been used for healing and recreation in several regions of the world.
Over 400 bioactive constituents, including more than 100 phytocannabinoids, have been …

Molecular mechanism of cannabinoids in cancer progression

C Pagano, G Navarra, L Coppola, M Bifulco… - International Journal of …, 2021 - mdpi.com
Cannabinoids are a family of heterogeneous compounds that mostly interact with receptors
eliciting several physiological effects both in the central and peripheral nervous systems and …

Modulation of the endocannabinoid system as a potential anticancer strategy

R Ramer, R Schwarz, B Hinz - Frontiers in pharmacology, 2019 - frontiersin.org
Currently, the involvement of the endocannabinoid system in cancer development and
possible options for a cancer-regressive effect of cannabinoids are controversially …

The current and potential application of medicinal cannabis products in dentistry

H Lowe, N Toyang, B Steele, J Bryant, W Ngwa… - Dentistry journal, 2021 - mdpi.com
Oral and dental diseases are a major global burden, the most common non-communicable
diseases (NCDs), and may even affect an individual's general quality of life and health. The …

Exploring the 1, 3-benzoxazine chemotype for cannabinoid receptor 2 as a promising anti-cancer therapeutic

N Gambacorta, V Gasperi, T Guzzo, FS Di Leva… - European Journal of …, 2023 - Elsevier
The discovery of selective agonists of cannabinoid receptor 2 (CB 2) is strongly pursued to
successfully tuning endocannabinoid signaling for therapeutic purposes. However, the …

[HTML][HTML] Disorders of cancer metabolism: The therapeutic potential of cannabinoids

D Sun, X Li, S Nie, J Liu, S Wang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abnormal energy metabolism, as one of the important hallmarks of cancer, was induced by
multiple carcinogenic factors and tumor-specific microenvironments. It comprises aerobic …

Synthetic cannabinoids nano-micelles for the management of triple negative breast cancer

K Greish, A Mathur, R Al Zahrani, S Elkaissi… - Journal of Controlled …, 2018 - Elsevier
Triple-negative breast cancer (TNBC) is a highly heterogeneous disease with poor
prognosis and inadequate therapeutic outcome. This contribution reports the use of a …