Naringenin: A potential flavonoid phytochemical for cancer therapy

M Motallebi, M Bhia, HF Rajani, I Bhia, H Tabarraei… - Life Sciences, 2022 - Elsevier
Naringenin is an important phytochemical which belongs to the flavanone group of
polyphenols, and is found mainly in citrus fruits like grapefruits and others such as tomatoes …

The therapeutic potential of naringenin: a review of clinical trials

B Salehi, PVT Fokou, M Sharifi-Rad, P Zucca… - Pharmaceuticals, 2019 - mdpi.com
Naringenin is a flavonoid belonging to flavanones subclass. It is widely distributed in several
Citrus fruits, bergamot, tomatoes and other fruits, being also found in its glycosides form …

[HTML][HTML] The anticancer mechanism of action of selected polyphenols in triple-negative breast cancer (TNBC)

R Farghadani, R Naidu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Breast cancer is a leadingcause of cancer-related deaths in women globally, with triple-
negative breast cancer (TNBC) being an aggressive subtype that lacks targeted therapies …

Naringenin as a potential immunomodulator in therapeutics

W Zeng, L Jin, F Zhang, C Zhang, W Liang - Pharmacological research, 2018 - Elsevier
Naringenin, a citrus flavonoid that possesses various biological activities, has emerged as a
potential therapeutic agent for the management of a variety of diseases. Studies using cell …

Combating oxidative stress disorders with citrus flavonoid: Naringenin

NH Zaidun, ZC Thent, A Abd Latiff - Life sciences, 2018 - Elsevier
The incidence of diseases related to oxidative stress disorders have been increased
dramatically. Alternatives medicine or the active compound extracted from the natural …

Naringenin and its derivatives—Health-promoting phytobiotic against resistant bacteria and fungi in humans

A Duda-Madej, J Stecko, J Sobieraj, N Szymańska… - Antibiotics, 2022 - mdpi.com
Naringenin is a trihydroxyflavanone present in large amount in different citrus fruits, eg,
oranges, pomelos, grapefruits, but also in tomatoes, fenugreek and coffee. It has a wide …

[HTML][HTML] Hesperidin and its aglycone hesperetin in breast cancer therapy: A review of recent developments and future prospects

KM Yap, M Sekar, YS Wu, SH Gan, NNIM Rani… - Saudi Journal of …, 2021 - Elsevier
Breast cancer (BC) has high incidence and mortality rates, making it a major global health
issue. BC treatment has been challenging due to the presence of drug resistance and the …

Flavonoids: structure–function and mechanisms of action and opportunities for drug development

S Safe, A Jayaraman, RS Chapkin, M Howard… - Toxicological …, 2021 - Springer
Flavonoids are polyphenolic phytochemicals produced in fruits, nuts and vegetables and
dietary consumption of these structurally diverse compounds is associated with multiple …

Comprehensive review on naringenin and naringin polyphenols as a potent anticancer agent

A Rauf, MA Shariati, M Imran, K Bashir… - … Science and Pollution …, 2022 - Springer
Though the incidence of several cancers in Western societies is regulated wisely, some
cancers such as breast, lung, and colorectal cancer are currently rising in many low-and …

Chemotherapeutic potential of hesperetin for cancer treatment, with mechanistic insights: A comprehensive review

M Sohel, H Sultana, T Sultana, M Al Amin, S Aktar… - Heliyon, 2022 - cell.com
Background Cancer has become a significant concern in the medical sector with increasing
disease complexity. Although some available conventional treatments are still a blessing for …