[PDF][PDF] Obesity as a risk factor for different types of cancer

N Tzenios - EPRA International Journal of Research and …, 2023 - researchgate.net
Over the last few decades, the incidence of obesity is increasing which is now recognized as
public health issue worldwide. Obesity has been associated with an elevated risk of several …

Obesity and colorectal cancer

M Bardou, AN Barkun, M Martel - Gut, 2013 - gut.bmj.com
Excess body weight, as defined by the body mass index (BMI), has been associated with
several diseases and includes subjects who are overweight (BMI≥ 25–29.9 kg/m2) or …

[HTML][HTML] Biology of colorectal cancer

F Arvelo, F Sojo, C Cotte - Ecancermedicalscience, 2015 - ncbi.nlm.nih.gov
Colorectal cancer is a serious health problem, a challenge for research, and a model for
studying the molecular mechanisms involved in its development. According to its incidence …

S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression

X Wang, Z Qiu, W Dong, Z Yang, J Wang, H Xu… - Cell Death & …, 2022 - nature.com
Angiogenesis is a fundamental process underlying the occurrence, growth and metastasis of
hepatocellular carcinoma (HCC), a prevalent tumour type with an extremely poor prognosis …

[HTML][HTML] Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer

J Zeng, ZH Tang, S Liu, SS Guo - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To compare the expression levels of interleukin (IL)-6 in colorectal cancer (CRC) tissues
and adjacent non-cancerous tissues, and analyse the correlation of IL-6 expression with the …

Autophagy and the insulin-like growth factor (IGF) system in colonic cells: implications for colorectal neoplasia

A Kasprzak - International journal of molecular sciences, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common human malignancies worldwide. Along
with apoptosis and inflammation, autophagy is one of three important mechanisms in CRC …

Triptolide decreases tumor‐associated macrophages infiltration and M2 polarization to remodel colon cancer immune microenvironment via inhibiting tumor‐derived …

X Jiang, G Cao, G Gao, W Wang… - Journal of cellular …, 2021 - Wiley Online Library
Colon cancer is a common and deadly human digestive tract malignant tumor with poor
prognosis. Immunotherapy has elicited tremendous success as a treatment modality for …

Proteomic approaches to decipher cancer cell secretome

J Brandi, M Manfredi, G Speziali, F Gosetti… - Seminars in Cell & …, 2018 - Elsevier
In this review, we give an overview of the actual proteomic approaches used in the study of
cancer cells secretome. In particular, we describe the proteomic strategies to decipher …

Antibody arrays in biomarker discovery

JJ Wilson, R Burgess, YQ Mao, S Luo, H Tang… - Advances in clinical …, 2015 - Elsevier
All of life is regulated by complex and organized chemical reactions that help dictate when to
grow, to move, to reproduce, and to die. When these processes go awry, or are interrupted …

Hypercoagulation in colorectal cancer: what can platelet indices tell us?

C Seretis, H Youssef, M Chapman - Platelets, 2015 - Taylor & Francis
Colorectal cancer, as all solid malignancies, is accompanied by changes in the haemostatic
mechanism favoring the establishment of a thrombotic potential, with platelets playing a key …