Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Reactive oxygen species (ROS) are considered to be chemically reactive with and
damaging to biomolecules including DNA, protein, and lipid, and excessive exposure to …

Resveratrol—a natural polyphenolic compound—was first discovered in the 1940s.
Although initially used for cancer therapy, it has shown beneficial effects against most …

Oxidative stress mediated by hyperglycaemia-induced generation of reactive oxygen
species (ROS) contributes significantly to the development and progression of diabetes and …

Reactive oxygen species (ROS) contribute to several aspects of vascular diseases including
ischemia–reperfusion injury, scavenging of nitric oxide, or stimulation of inflammation and …

The NADPH oxidase (NOX) family of enzymes produces ROS as their sole function and is
becoming recognized as key modulators of signal transduction pathways with a …

Sortilin has been positively correlated with vascular disorders in humans. No study has yet
evaluated the possible direct effect of sortilin on vascular function. We used pharmacological …

Diabetes mellitus is a common disease that affects 3–5% of the general population in Italy.
In some countries of northern Europe or in North America, it can even affect 6–8% of the …

Abstract'Oxidative stress' is a term defining states of elevated reactive oxygen species (ROS)
levels. Normally, ROS control several physiological processes, such as host defence …

OBJECTIVE Hyperglycemia induces reactive oxygen species (ROS) and apoptosis in
cardiomyocytes, which contributes to diabetic cardiomyopathy. The present study was to …