[HTML][HTML] Recent advances in biomedical engineering of nano-hydroxyapatite including dentistry, cancer treatment and bone repair

M Du, J Chen, K Liu, H Xing, C Song - Composites Part B: Engineering, 2021 - Elsevier
Hydroxyapatite (HAp) has significant biological activity, degradability, and osteoconductivity.
In recent decades, it has been widely used in dentistry, anti-tumour drug carriers, and …

Hydroxyapatite nanoparticles for improved cancer theranostics

S Kargozar, S Mollazadeh, F Kermani… - Journal of Functional …, 2022 - mdpi.com
Beyond their well-known applications in bone tissue engineering, hydroxyapatite
nanoparticles (HAp NPs) have also been showing great promise for improved cancer …

Piperine: an emerging biofactor with anticancer efficacy and therapeutic potential

HL Wiraswati, IF Ma'ruf, J Sharifi‐Rad, D Calina - BioFactors, 2025 - Wiley Online Library
Anticancer drug discovery needs serious attention to overcome the high mortality rate
caused by cancer. There are still many obstacles to treating this disease, such as the high …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Formulation of piperine–chitosan-coated liposomes: Characterization and in vitro cytotoxic evaluation

SS Imam, S Alshehri, MA Altamimi, A Hussain… - Molecules, 2021 - mdpi.com
The present research work is designed to prepare and evaluate piperine liposomes and
piperine–chitosan-coated liposomes for oral delivery. Piperine (PPN) is a water-insoluble …

Pectin coated nanostructured lipid carriers for targeted piperine delivery to hepatocellular carcinoma

EMM Shehata, MA Gowayed, SO El-Ganainy… - International Journal of …, 2022 - Elsevier
Piperine (PIP) is a herbal drug with well-known anticancer activity against different types of
cancer including hepatocellular carcinoma. However, low aqueous solubility and extensive …

Hydroxyapatite biobased materials for treatment and diagnosis of cancer

MC De Lama-Odría, LJ Del Valle… - International journal of …, 2022 - mdpi.com
Great advances in cancer treatment have been undertaken in the last years as a
consequence of the development of new antitumoral drugs able to target cancer cells with …

Treating colon cancers with a non-conventional yet strategic approach: An overview of various nanoparticulate systems

NA Bhaskaran, L Kumar - Journal of Controlled Release, 2021 - Elsevier
Regardless of progress in therapy management which are developed for colon cancer (CC),
it remains the third most common cause of mortality due to cancers around the world …

Drug-releasing antibacterial coating made from nano-hydroxyapatite using the sonocoating method

K AbouAitah, M Bil, E Pietrzykowska, U Szałaj… - Nanomaterials, 2021 - mdpi.com
Medical implant use is associated with a risk of infection caused by bacteria on their surface.
Implants with a surface that has both bone growth-promoting properties and antibacterial …

Anti-inflammatory and antioxidant effects of nanoformulations composed of metal-organic frameworks delivering rutin and/or piperine natural agents

K AbouAitah, IM Higazy, A Swiderska-Sroda… - Drug Delivery, 2021 - Taylor & Francis
Plant-derived natural medicines have been extensively studied for anti-inflammatory or
antioxidant properties, but challenges to their clinical use include low bioavailability, poor …