Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired
weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk …

Background Post‐intensive care syndrome (PICS) encompasses physical, cognition, and
mental impairments persisting after intensive care unit (ICU) discharge. Ultimately it …

Following the new ESPEN Standard Operating Procedures, the previous guidelines to
provide best medical nutritional therapy to critically ill patients have been updated. These …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Background Muscular weakness and/or muscle wasting is recognized as a key medical
problem in critically ill patients on intensive care units (ICUs) worldwide. Methods and …

Background Growing evidence associates organ dysfunction (s) with impaired metabolism
in sepsis. Recent research has increased our understanding of the role of substrate …

Background Controversy exists about the timing of the initiation of parenteral nutrition in
critically ill adults in whom caloric targets cannot be met by enteral nutrition alone. Methods …

The importance of the interplay between inflammation and nutrition has generated much
interest in recent times. Inflammation has been identified as a key driver for disease-related …

Defects in autophagy have been linked to a wide range of medical illnesses, including
cancer as well as infectious, neurodegenerative, inflammatory, and metabolic diseases …

Importance Inflammation is a key driver of malnutrition during illness and is often
accompanied by metabolic effects, including insulin resistance and reduction of appetite …