[HTML][HTML] MBOAT7 is anchored to endomembranes by six transmembrane domains

A Caddeo, O Jamialahmadi, G Solinas, A Pujia… - Journal of Structural …, 2019 - Elsevier
Membrane bound O-acyltransferase domain-containing 7 (MBOAT7, also known as LPIAT1)
is a protein involved in the acyl chain remodeling of phospholipids via the Lands' cycle. The …

Life at the border: Adaptation of proteins to anisotropic membrane environment

ID Pogozheva, HI Mosberg, AL Lomize - Protein Science, 2014 - Wiley Online Library
This review discusses main features of transmembrane (TM) proteins which distinguish them
from water‐soluble proteins and allow their adaptation to the anisotropic membrane …

TMSEG: Novel prediction of transmembrane helices

M Bernhofer, E Kloppmann, J Reeb… - … Structure, Function, and …, 2016 - Wiley Online Library
Transmembrane proteins (TMPs) are important drug targets because they are essential for
signaling, regulation, and transport. Despite important breakthroughs, experimental structure …

Evaluation of transmembrane helix predictions in 2014

J Reeb, E Kloppmann, M Bernhofer… - … Structure, Function, and …, 2015 - Wiley Online Library
Experimental structure determination continues to be challenging for membrane proteins.
Computational prediction methods are therefore needed and widely used to supplement …

A functional genomic analysis of Arabidopsis thaliana PP2C clade D

A Tovar-Mendez, JA Miernyk, E Hoyos, DD Randall - Protoplasma, 2014 - Springer
In the reference dicot plant Arabidopsis thaliana, the PP2C family of P-protein phosphatases
includes the products of 80 genes that have been separated into ten multi-protein clades …

Prediction enhancement of residue real-value relative accessible surface area in transmembrane helical proteins by solving the output preference problem of machine …

F Xiao, HB Shen - Journal of chemical information and modeling, 2015 - ACS Publications
The α-helical transmembrane proteins constitute 25% of the entire human proteome space
and are difficult targets in high-resolution wet-lab structural studies, calling for accurate …

Topology based identification and comprehensive classification of four-transmembrane helix containing proteins (4TMs) in the human genome

MM Attwood, A Krishnan, V Pivotti, S Yazdi, MS Almén… - BMC genomics, 2016 - Springer
Background Membrane proteins are key components in a large spectrum of diverse
functions and thus account for the major proportion of the drug-targeted portion of the …

[图书][B] Statistics for bioinformatics: methods for multiple sequence alignment

J Thompson - 2016 - books.google.com
Statistics for Bioinformatics: Methods for Multiple Sequence Alignment provides an in-depth
introduction to the most widely used methods and software in the bioinformatics field. With …

In silico evaluation of the influence of the translocon on partitioning of membrane segments

D Tessier, S Laroum, B Duval, EM Rath, WB Church… - BMC …, 2014 - Springer
Background The locations of the TM segments inside the membrane proteins are the
consequence of a cascade of several events: the localizing of the nascent chain to the …

[PDF][PDF] Ion Move Brownian Dynamics (IMBD): Simulations of Ion Transport

M Kurczyńska, M Kotulska - Acta of Bioengineering and …, 2014 - bibliotekanauki.pl
Purpose: Comparison of the computed characteristics and physiological measurement of ion
transport through transmembrane proteins could be a useful method to assess the quality of …