Fungal pathogens depend on sophisticated gene expression programs for successful
infection. A crucial component is RNA regulation mediated by RNA-binding proteins (RBPs) …

Aneuploidy produces myriad consequences in health and disease, yet models of the
deleterious effects of chromosome amplification are still widely debated. To distinguish the …

Furfural is a major inhibitor found in lignocellulosic hydrolysate, a promising feedstock for
the biofermentation industry. In this study, we aimed to investigate the potential impact of this …

Pathogenic fungi hide from their hosts by camouflage, obscuring immunogenic cell wall
components such as beta-glucan with innocuous coverings such as mannoproteins and …

Proteins containing a RNB domain, originally identified in Escherichia coli RNase II, are
widely present throughout the tree of life. Many RNB proteins have 3′-5 …

RNA-binding proteins (RBPs) play critical cellular roles by mediating various stages of RNA
life cycles. Ssd1, an RBP with pleiotropic effects, has been implicated in aneuploidy …

Pervasive transcription of eukaryotic genomes generates non-coding transcripts with
regulatory potential. We examined the effects of non-coding antisense transcription on the …

Profiling the repertoire of proteins associated with a given mRNA during the cell cycle is
unstudied. Furthermore, it is easier to ask and answer what mRNAs a specific protein might …

Copy-number variants (CNVs) are large-scale amplifications or deletions of DNA that can
drive rapid adaptive evolution and result in large-scale changes in gene expression …

The fungal cell wall provides protection and structure and is an important target for
antifungal compounds. A mitogen-activated protein (MAP) kinase cascade termed the cell …