Intervertebral disc diseases PART 2: a review of the current diagnostic and treatment strategies for intervertebral disc disease

PH Wu, HS Kim, IT Jang - International journal of molecular sciences, 2020 - mdpi.com
With an aging population, there is a proportional increase in the prevalence of intervertebral
disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and …

[HTML][HTML] Cell therapy for intervertebral disc repair: clinical perspective

D Sakai, J Schol - Journal of orthopaedic translation, 2017 - Elsevier
Low back pain is the main cause of disability and is associated with intervertebral disc
degeneration. Contemporary treatments are limited to palliative therapeutics or aggressive …

The Pfirrmann classification of lumbar intervertebral disc degeneration: an independent inter-and intra-observer agreement assessment

J Urrutia, P Besa, M Campos, P Cikutovic… - European Spine …, 2016 - Springer
Purpose Grading inter-vertebral disc degeneration (IDD) is important in the evaluation of
many degenerative conditions, including patients with low back pain. Magnetic resonance …

Cell therapy for intervertebral disc herniation and degenerative disc disease: clinical trials

J Schol, D Sakai - International orthopaedics, 2019 - Springer
Low back pain is the primary cause of disability and is highly associated with progression of
intervertebral disc degeneration. Current treatment options are limited and fail to address the …

MicroRNA-155 suppressed cholesterol-induced matrix degradation, pyroptosis and apoptosis by targeting RORα in nucleus pulposus cells

T Qin, J Yan, S Li, X Lin, J Wu, Z Huang, C Zhang… - Cellular …, 2023 - Elsevier
Intervertebral disc degeneration (IDD) is associated with low back pain, yet its inherent
mechanism remains obscure. Hypercholesteremia was regarded as a risk factor for IDD, and …

Review of dynamic contrast‐enhanced MRI: technical aspects and applications in the musculoskeletal system

P Sujlana, J Skrok, LM Fayad - Journal of Magnetic Resonance …, 2018 - Wiley Online Library
Although postcontrast imaging has been used for many years in musculoskeletal imaging,
dynamic contrast enhanced (DCE) MRI is not routinely used in many centers around the …

Diagnostic role of magnetic resonance imaging in low back pain caused by vertebral endplate degeneration

RU Din, X Cheng, H Yang - Journal of Magnetic Resonance …, 2022 - Wiley Online Library
Low back pain (LBP) is a common health issue worldwide with a huge economic burden on
healthcare systems. In the United States alone, the cost is estimated to be $100 billion each …

Modic I changes size increase from supine to standing MRI correlates with increase in pain intensity in standing position: uncovering the “biomechanical stress” and “ …

A Splendiani, F Bruno, C Marsecano, F Arrigoni… - European Spine …, 2019 - Springer
Purpose To evaluate the relationship between degenerative disc, endplate Modic changes
(MC) type I, and pain during upright weight-bearing MRI scan of the lumbar spine in a cohort …

Morphometry of the lower lumbar intervertebral discs and endplates: comparative analyses of new MRI data with previous findings

R Tang, C Gungor, RF Sesek, KB Foreman… - European Spine …, 2016 - Springer
Purpose Variability of the human lower lumbar geometry is related to complications of disc
arthroplasty surgery. Accurate morphometric descriptions are essential for the design of …

[HTML][HTML] Analysis of correlation between vertebral endplate change and lumbar disc degeneration

L Xiao, C Ni, J Shi, Z Wang, S Wang… - … medical journal of …, 2017 - ncbi.nlm.nih.gov
Analysis of Correlation Between Vertebral Endplate Change and Lumbar Disc Degeneration -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …