Unique Properties of Apicomplexan Mitochondria

IM Lamb, IC Okoye, MW Mather… - Annual review of …, 2023 - annualreviews.org
Apicomplexan parasites constitute more than 6,000 species infecting a wide range of hosts.
These include important pathogens such as those causing malaria and toxoplasmosis. Their …

Ribosome specialization in Protozoa parasites

CC Rodríguez-Almonacid, MK Kellogg… - International Journal of …, 2023 - mdpi.com
Ribosomes, in general, are viewed as constitutive macromolecular machines where protein
synthesis takes place; however, this view has been recently challenged, supporting the …

Apicomplexan mitoribosome from highly fragmented rRNAs to a functional machine

C Wang, S Kassem, REO Rocha, P Sun… - Nature …, 2024 - nature.com
The phylum Apicomplexa comprises eukaryotic parasites that cause fatal diseases affecting
millions of people and animals worldwide. Their mitochondrial genomes have been …

DNA N-glycosylases Ogg1 and EndoIII as components of base excision repair in Plasmodium falciparum organelles

A Tiwari, N Verma, H Shukla, S Mishra… - International Journal for …, 2024 - Elsevier
The integrity of genomes of the two crucial organelles of the malaria parasite—an apicoplast
and mitochondrion in each cell− must be maintained by DNA repair mediated by proteins …

[HTML][HTML] Plasmodium falciparum Mitochondrial Complex III, the Target of Atovaquone, Is Essential for Progression to the Transmissible Sexual Stages

PK Sheokand, S Pradhan, AE Maclean… - International Journal of …, 2024 - mdpi.com
The Plasmodium falciparum mitochondrial electron transport chain (mETC) is responsible
for essential metabolic pathways such as de novo pyrimidine synthesis and ATP synthesis …

Comparative 3D ultrastructure of Plasmodium falciparum gametocytes

F Evers, R Roverts, C Boshoven… - Nature …, 2025 - nature.com
Despite the enormous significance of malaria parasites for global health, some basic
features of their ultrastructure remain obscure. Here, we apply high-resolution volumetric …

Partial Characterization of Plasmodium falciparum Genes Implicated in Altered Artemisinin Stress Response

CF Simmons - 2023 - search.proquest.com
Malaria is a parasitic illness caused by the Plasmodium spp., with an estimated 247 million
malaria cases reported in 2021 across 84 endemic countries. Treatment of the deadliest …