The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery

NA di Meo, F Lasorsa, M Rutigliano… - Expert Review of …, 2023 - Taylor & Francis
Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …

[HTML][HTML] Adipose Tissues Have Been Overlooked as Players in Prostate Cancer Progression

KT Liermann-Wooldrik, EA Kosmacek… - International journal of …, 2024 - mdpi.com
Obesity is a common risk factor in multiple tumor types, including prostate cancer. Obesity
has been associated with driving metastasis, therapeutic resistance, and increased …

New insights into lipid metabolism and prostate cancer

Z Zhang, W Wang, P Kong, K Feng… - International …, 2023 - spandidos-publications.com
Prostate cancer (PCa) is the most common malignant tumor of the male urological system
and poses a severe threat to the survival of middle‑aged and elderly males worldwide. The …

Pretreatment of human retinal pigment epithelial cells with sterculic acid forestalls fenretinide-induced apoptosis

S William, T Duncan, TM Redmond - Scientific Reports, 2022 - nature.com
The ratio of saturated to monounsaturated fatty acids, thought to play a critical role in many
cellular functions, is regulated by stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in …

Lipid metabolism, amino acid metabolism, and prostate cancer: a crucial metabolic journey

L Chen, YX Xu, YS Wang, JL Zhou - Asian Journal of Andrology, 2024 - journals.lww.com
Prostate cancer (PCa) is one of the most common malignancies in males worldwide, and its
development and progression involve the regulation of multiple metabolic pathways …

[HTML][HTML] Identifying Key Genes as Progression Indicators of Prostate Cancer with Castration Resistance Based on Dynamic Network Biomarker Algorithm and …

S Liu, Y Hu, F Liu, Y Jiang, H Wang, X Wu, D Hu - Biomedicines, 2024 - mdpi.com
Background: Androgen deprivation therapy (ADT) is the mainstay of treatment for prostate
cancer, yet dynamic molecular changes from hormone-sensitive to castration-resistant states …

In vitro antitumor effects of aqueous extract and protease inhibitors from Sterculia striata st. Hil. et naud and metabolite profiling

TFB Junior, NM Lima, GP Carli… - Natural Product …, 2024 - Taylor & Francis
The present study aims to assess the cytotoxic effect of the aqueous and protease inhibitors
extracts of Sterculia striata on breast cancer cell lines. The in vitro results showed significant …

Sterculic acid inhibits fenretinide-induced apoptosis in human retinal pigment epithelial cells

S William, T Duncan, TM Redmond - 2022 - researchsquare.com
The ratio of saturated to monounsaturated fatty acids, thought to play a critical role in many
cellular functions, is regulated by stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in …

[PDF][PDF] Therapeutic Potential of Sterculia Seeds in Metabolic Syndrome

MG Sánchez-Otero… - Complementary … - uniquescientificpublishers.com
Metabolic syndrome (MetS) represents a significant health concern globally, necessitating
diverse strategies for its management. Non-pharmacological approaches, including lifestyle …

Lipid unsaturation in ovarian cancer

G Zhao - 2022 - search.proquest.com
Fat represents an important source of energy for ovarian cancer (OC) cells and is supplied
either through import from the tumor milieu or via de novo lipogenesis. During fast tumor …