[HTML][HTML] Mechanisms of ADAMTS13 regulation

V DeYoung, K Singh, CA Kretz - Journal of Thrombosis and Haemostasis, 2022 - Elsevier
Recombinant ADAMTS13 is currently undergoing clinical trials as a treatment for hereditary
thrombotic thrombocytopenic purpura, a lethal microvascular condition resulting from …

[HTML][HTML] Von Willebrand factor: A key glycoprotein involved in thrombo-inflammatory complications of COVID-19

S Choudhary, K Sharma, PK Singh - Chemico-Biological Interactions, 2021 - Elsevier
COVID-19 is an ongoing public health emergency that has affected millions of people
worldwide and is still a threat to many more. One of the pathophysiological features of …

Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome

B Simbrunner, IF Villesen, B Scheiner… - Hepatology …, 2023 - Springer
Background and aims Endothelial dysfunction and portal hypertension (PH) are reflected by
increased von Willebrand factor antigen (VWF-Ag) levels in advanced chronic liver disease …

ADAMTS-13/von Willebrand factor ratio: A prognostic biomarker for portal vein thrombosis in compensated cirrhosis. A prospective observational study

M Sacco, M Tardugno, S Lancellotti, A Ferretti… - Digestive and Liver …, 2022 - Elsevier
Background and aims In cirrhosis, decreased portal flow velocity, thrombophilia factors, and
portal hypertension are considered risk factors for portal vein thrombosis (PVT). In cirrhosis …

[HTML][HTML] Clinical significance of substantially elevated von Willebrand factor antigen levels in patients with advanced chronic liver disease

K Pomej, B Scheiner, L Balcar, RJ Nussbaumer… - Digestive and Liver …, 2022 - Elsevier
Abstract Background Von Willebrand factor antigen (VWF) is a non-invasive marker for
clinically significant portal hypertension (HVPG≥ 10 mmHg) and confers HVPG …

Role of perturbated hemostasis in Masld and its correlation with adipokines

S Pezzino, T Luca, M Castorina, S Puleo, S Latteri… - Life, 2024 - mdpi.com
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD)
continues to rise, making it one of the most prevalent chronic liver disorders. MASLD …

Von Willebrand Factor as a biomarker for liver disease–an update

A Elhence - Journal of Clinical and Experimental Hepatology, 2023 - Elsevier
The von Willebrand factor (vWF) is best known for its role in the hemostatic pathway, aiding
platelet adhesion and aggregation, as well as circulating along with coagulation factor VIII …

Ancient herbal formula Mahuang Lianqiao Chixiaodou decoction protects acute and acute-on-chronic liver failure via inhibiting von Willebrand factor signaling

J Lin, Q Ling, L Yan, B Chen, F Wang, Y Qian, Y Gao… - Cells, 2022 - mdpi.com
Background: Acute liver failure (ALF) and acute-on-chronic liver failure (ACLF) are
characterized by systemic inflammation and high mortality, but there is no effective clinical …

Serum 25‐hydroxyvitamin D and C‐reactive protein and plasma von Willebrand concentrations in 23 dogs with chronic hepatopathies

YM Ambrosini, C Piedra‐Mora… - Journal of Veterinary …, 2022 - Wiley Online Library
Background Serum concentrations of 25‐hydroxyvitamin D (25 (OH) VD) and C‐reactive
protein (CRP) and von Willebrand's factor (vWF) concentration correlate with histopathologic …

Rodenticide (yellow phosphorus poison)-induced hepatotoxicity in India: constraints during management

CE Eapen, J Venkataraman - Journal of Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Acute hepatic dysfunction is categorized as acute liver injury (ALI) ie presence of
coagulopathy, with no encephalopathy and acute liver failure (ALF) ie, presence of …