[HTML][HTML] Colon cancer and colorectal cancer: Prevention and treatment by potential natural products

MR Islam, S Akash, MM Rahman, FT Nowrin… - Chemico-biological …, 2022 - Elsevier
Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

Plant secondary metabolites as anticancer agents: successes in clinical trials and therapeutic application

AML Seca, DCGA Pinto - International journal of molecular sciences, 2018 - mdpi.com
Cancer is a multistage process resulting in an uncontrolled and abrupt division of cells and
is one of the leading causes of mortality. The cases reported and the predictions for the near …

Cellular and molecular mechanisms of curcumin in prevention and treatment of disease

SS Patel, A Acharya, RS Ray, R Agrawal… - Critical reviews in …, 2020 - Taylor & Francis
Curcumin is a naturally occurring polyphenolic compound present in rhizome of Curcuma
longa belonging to the family zingiberaceae. Growing experimental evidence revealed that …

Mechanism of apoptosis induced by curcumin in colorectal cancer

NI Ismail, I Othman, F Abas, N H. Lajis… - International journal of …, 2019 - mdpi.com
Colorectal cancer (CRC) is among the top three cancer with higher incident and mortality
rate worldwide. It is estimated that about over than 1.1 million of death and 2.2 million new …

Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen species–independent mitochondrial apoptotic pathway in Smad4 and p53 …

A Agarwal, A Kasinathan, R Ganesan… - Nutrition Research, 2018 - Elsevier
Curcumin is a natural dietary polyphenol compound that has various pharmacological
activities such as antiproliferative and cancer-preventive activities on tumor cells. Indeed, the …

Protective and detoxifying effects conferred by dietary selenium and curcumin against AFB1-mediated toxicity in livestock: a review

A Limaye, RC Yu, CC Chou, JR Liu, KC Cheng - Toxins, 2018 - mdpi.com
Aflatoxin B1 (AFB1), among other aflatoxins of the aflatoxin family, is the most carcinogenic
and hazardous mycotoxin to animals and human beings with very high potency leading to …

Curcumin mitigates AFB1-induced hepatic toxicity by triggering cattle antioxidant and anti-inflammatory pathways: A whole transcriptomic in vitro study

M Pauletto, M Giantin, R Tolosi, I Bassan, A Barbarossa… - Antioxidants, 2020 - mdpi.com
Aflatoxin B1 (AFB1) toxicity in livestock and human beings is a major economic and health
concern. Natural polyphenolic substances with antioxidant properties have proven to be …

Polyphenols: Major regulators of key components of DNA damage response in cancer

M Majidinia, A Bishayee, B Yousefi - DNA repair, 2019 - Elsevier
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …

Curcumin encapsulation in nanostructures for cancer therapy: A 10-year overview

NA D'Angelo, MA Noronha, IS Kurnik… - International journal of …, 2021 - Elsevier
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa
Linn.(turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is …

Curcumin: A therapeutic strategy for colorectal cancer?

VR de Porras, L Layos, E Martínez-Balibrea - Seminars in cancer biology, 2021 - Elsevier
Colorectal cancer (CRC) is the second cause of cancer death worldwide. The metastatic
disease is mainly treated with aggressive therapies consisting on combinations of cytotoxic …