Lung cancer is the leading cause of global cancer-related mortality resulting in∼ 1.8 million
deaths annually. Systemic, molecular targeted, and immune therapies have provided …

Patient-derived organoids (PDO), based on the advanced three-dimensional (3D) culture
technology, can provide more relevant physiological and pathological cancer models, which …

The thyroid maintains systemic homeostasis by regulating serum thyroid hormone
concentrations. Here we report the establishment of three-dimensional (3D) organoids from …

Tumor organoids have been pushed forward as advanced model systems for in vitro
oncology drug testing, with the eventual goal to direct personalized cancer treatments …

Background Recent advancements in 3-dimensional patient-derived organoid models have
revolutionized the field of cancer biology. There is an urgent need for development of …

Head and neck squamous cell carcinomas (HNSCCs) are introduced as the sixth most
common cancer in the world. Detection of predictive biomarkers improve early diagnosis …

Radiation therapy and platinum-based chemotherapy are common treatments for lung
cancer patients. Several factors are considered for the low overall survival rate of lung …

Head and neck cancer (HNC) is one of the most common cancers on the planet, with
approximately 600,000 new cases diagnosed and 300,000 deaths every year. Research …

Patient‐derived cancer disease models conserve many key features of the original human
cancers, potentially allowing higher predictive power than traditional cell line models …

Gastric organoids are models created in the laboratory using stem cells and sophisticated
three-dimensional cell culture techniques. These models have shown great promise in …