Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
HLA variation and antigen presentation in COVID-19 and SARS-CoV-2 infection
DG Augusto, JA Hollenbach - Current opinion in immunology, 2022 - Elsevier
Highlights•Variation in both HLA and SARS-CoV-2 impact antigen presentation to T
cells.•HLA variation influences COVID-19 outcomes and T-cell responses to SARS-CoV …
cells.•HLA variation influences COVID-19 outcomes and T-cell responses to SARS-CoV …
Association between HLA-C alleles and COVID-19 severity in a pilot study with a Spanish Mediterranean Caucasian cohort
L Vigón, M Galán, M Torres, AJ Martín-Galiano… - PloS One, 2022 - journals.plos.org
The clinical presentations of COVID-19 may range from an asymptomatic or mild infection to
a critical or fatal disease. Several host factors such as elderly age, male gender, and …
a critical or fatal disease. Several host factors such as elderly age, male gender, and …
The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review
T Hoseinnezhad, N Soltani, S Ziarati… - Journal of Clinical …, 2024 - Wiley Online Library
Background The COVID‐19 pandemic has had a profound global impact, with variations in
susceptibility, severity, and mortality rates across different regions. While many factors can …
susceptibility, severity, and mortality rates across different regions. While many factors can …
The role of HLA genotypes in understanding the pathogenesis of severe COVID-19
F Arab, S Mollazadeh, F Ghayourbabaei… - Egyptian Journal of …, 2023 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused human tragedy
through the global spread of the viral pathogen SARS-CoV-2. Although the underlying …
through the global spread of the viral pathogen SARS-CoV-2. Although the underlying …
The association of human leucocyte antigen (HLA) alleles with COVID‐19 severity: a systematic review and meta‐analysis
Due to their pivotal role in orchestrating the immune response, HLA loci were recognized as
candidates for genetic association studies related to the severity of COVID‐19. Since the …
candidates for genetic association studies related to the severity of COVID‐19. Since the …
The Influence of HLA Polymorphisms on the Severity of COVID-19 in the Romanian Population
In this study, we aimed to investigate whether specific HLA alleles found in patients from
Romania and the Republic of Moldova were associated with the severity of COVID-19 …
Romania and the Republic of Moldova were associated with the severity of COVID-19 …
[HTML][HTML] Association of human leukocyte antigen class I and class II alleles and haplotypes in COVID-19 infection in a western Indian population
AS Tripathy, P Wagh, S Vishwakarma… - Infection, Genetics …, 2023 - ncbi.nlm.nih.gov
In December 2022 an interesting and potentially important review article published in this
journal entitled “Genome-wide association studies of COVID-19: Connecting the dots” …
journal entitled “Genome-wide association studies of COVID-19: Connecting the dots” …
A bioinformatic analysis of T-cell epitope diversity in SARS-CoV-2 variants: association with COVID-19 clinical severity in the United States population
GJ Kim, JH Elnaggar, M Varnado, AK Feehan… - Frontiers in …, 2024 - frontiersin.org
Long-term immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) requires the identification of T-cell epitopes affecting host immunogenicity. In this …
2) requires the identification of T-cell epitopes affecting host immunogenicity. In this …
Immunoinformatics approach of epitope prediction for SARS-CoV-2
N Awad, RH Mohamed, NI Ghoneim… - Journal of Genetic …, 2022 - Elsevier
Background The novel coronavirus (SARS-CoV-2) caused lethal infections worldwide
during an unprecedented pandemic. Identification of the candidate viral epitopes is the first …
during an unprecedented pandemic. Identification of the candidate viral epitopes is the first …