The 3D microarchitecture of the cardiac muscle underlies the mechanical and electrical
properties of the heart. Cardiomyocytes are arranged helically through the depth of the wall …

The complex and highly organized structural arrangement of some five billion
cardiomyocytes directs the coordinated electrical activity and mechanical contraction of the …

Tagged MRI and finite-element (FE) analysis are valuable tools in analyzing cardiac
mechanics. To determine systolic material parameters in three-dimensional stress-strain …

Objective: The human heart is composed of a helical network of muscle fibers organized to
form sheets that are separated by cleavage planes responsible for the orthotropic …

Motion of the heart has complicated in vivo applications of cardiac diffusion MRI and
diffusion tensor imaging (DTI), especially in small animals such as rats where ultra-high …

This study aimed to investigate postinfarct left ventricular (LV) fiber structural alterations by
ex vivo diffusion tensor imaging (DTI) in a porcine heart model. In vivo cardiac MR imaging …

The cardiac muscle architecture lies at the basis of the mechanical and electrical properties
of the heart, and dynamic alterations in fiber structure are known to be of prime importance …

Systematic studies of cardiac structure-function relationships to date have been hindered by
the intrinsic complexity and variability of in vivo and ex vivo model systems. Thus, we set out …

Background We examined the dynamic response of the myocardium to infarction in a
longitudinal porcine study using relaxometry, functional as well as diffusion cardiovascular …

Background Knowledge of the three-dimensional (3D) infarct structure and fiber orientation
remodeling is essential for complete understanding of infarct pathophysiology and post …