Proteomics: technologies and their applications

B Aslam, M Basit, MA Nisar, M Khurshid… - Journal of …, 2016 - academic.oup.com
Proteomics involves the applications of technologies for the identification and quantification
of overall proteins present content of a cell, tissue or an organism. It supplements the other …

Isobaric labeling-based relative quantification in shotgun proteomics

N Rauniyar, JR Yates III - Journal of proteome research, 2014 - ACS Publications
Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …

[HTML][HTML] Proteomics: challenges, techniques and possibilities to overcome biological sample complexity

K Chandramouli, PY Qian - Human genomics and proteomics: HGP, 2009 - ncbi.nlm.nih.gov
Proteomics is the large-scale study of the structure and function of proteins in complex
biological sample. Such an approach has the potential value to understand the complex …

High-throughput proteomics and AI for cancer biomarker discovery

Q Xiao, F Zhang, L Xu, L Yue, OL Kon, Y Zhu… - Advanced drug delivery …, 2021 - Elsevier
Biomarkers are assayed to assess biological and pathological status. Recent advances in
high-throughput proteomic technology provide opportunities for developing next generation …

Proteomics of integral membrane proteins theory and application

AE Speers, CC Wu - Chemical reviews, 2007 - ACS Publications
Integral membrane proteins (IMPs) lie at the critical junctions between intracellular
compartments and cells and their environment. As such, IMPs are in a unique position to …

The neuroproteomics of schizophrenia

JA English, K Pennington, MJ Dunn, DR Cotter - Biological psychiatry, 2011 - Elsevier
Proteomics is the study of global gene expression of an organ, body system, fluid, or cellular
compartment at the protein level. Proteomic findings are reflective of complex gene× …

A multiplexed quantitative strategy for membrane proteomics: opportunities for mining therapeutic targets for autosomal dominant polycystic kidney disease

CL Han, CW Chien, WC Chen, YR Chen, CP Wu… - Molecular & Cellular …, 2008 - ASBMB
Toward multiplexed, comprehensive, and robust quantitation of the membrane proteome, we
report a strategy combining gel-assisted digestion, iTRAQ (isobaric tags for relative and …

iTRAQ reagent-based quantitative proteomic analysis on a linear ion trap mass spectrometer

TJ Griffin, H Xie, S Bandhakavi, J Popko… - Journal of proteome …, 2007 - ACS Publications
For proteomic analysis using tandem mass spectrometry, linear ion trap instruments provide
unsurpassed sensitivity but unreliably detect low mass peptide fragments, precluding their …

BASP1 promotes apoptosis in diabetic nephropathy

MD Sanchez-Nino, AB Sanz, C Lorz… - Journal of the …, 2010 - journals.lww.com
Apoptosis contributes to the development of diabetic nephropathy (DN), but the mechanisms
that lead to diabetes-induced cell death are not fully understood. Here, we combined a …

Blood-related proteomics

G Liumbruno, A D'Alessandro, G Grazzini, L Zolla - Journal of proteomics, 2010 - Elsevier
Blood-related proteomics is an emerging field, recently gaining momentum. Indeed, a wealth
of data is now available and a plethora of groups has contributed to add pieces to the jigsaw …