The uptake and metabolism of nutrients support fundamental cellular process from
bioenergetics to biomass production and cell fate regulation. While many studies of cell …

Metabolic reprogramming in cancer is not only a biological hallmark but also reveals
treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment …

Historically, cancer research and therapy have focused on malignant cells and their tumor
microenvironment. However, the vascular, lymphatic and nervous systems establish long …

In recent years dietary interventions have become a promising tool in cancer treatment and
have demonstrated a powerful ability to alter metabolism and tumor growth, development …

Intermittent fasting (IF), time-restricted eating (TRE) and fasting-mimicking diets (FMD) are
gaining popularity as weight loss programs. As such, the timing and frequency of meals …

Overnutrition is a risk factor for various human diseases, including neurodegenerative
diseases, metabolic disorders, and cancers. Therefore, targeting overnutrition represents a …

Background More than ten randomized clinical trials are being tested to evaluate the
efficacy, effectiveness and safety of a fasting-mimicking diet (FMD) combined with different …

Research on precancers, as defined as at-risk tissues and early lesions, is of high
significance given the effectiveness of early intervention. We discuss the need for risk …

Targeting altered tumor cell metabolism might provide an attractive opportunity for patients
with acute myeloid leukemia (AML). An amino acid dropout screen on primary leukemic …

A potential target of precision nutrition in cancer therapeutics is the micronutrient selenium
(Se). Se is metabolized and incorporated as the amino acid selenocysteine (Sec) into 25 …