In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Liver transplantation offers live-saving therapy for patients with complications of cirrhosis
and stage T2 hepatocellular carcinoma. The demand for organs far outstrips the supply, and …

Summary The EASL Clinical Practice Guidelines (CPGs) on the management of hepatic
encephalopathy (HE) present evidence-based answers to a set of relevant questions (where …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

The first consensus report of the working party of the Asian Pacific Association for the Study
of the Liver (APASL) set up in 2004 on acute-on-chronic liver failure (ACLF) was published …

Acute-on-Chronic Liver Failure Acute decompensation in patients with chronic liver disease
is called acute-on-chronic liver failure. Usually, systemic inflammation from infection or an …

Background & Aims Liver transplantation for patients with acute-on-chronic liver failure
(ACLF) with 3 or more failing organs (ACLF-3) is controversial. We compared liver waitlist …

Background & Aims Liver transplantation (LT) has been proposed as an effective salvage
therapy even for the sickest patients with acute-on-chronic liver failure (ACLF). This large …

Alcohol-related liver disease (ALD), which includes a range of disorders of different severity
and is one of the most prevalent types of liver disease worldwide, has recently regained …

The term acute-on-chronic liver failure (ACLF) defines an abrupt and life-threatening
worsening of clinical conditions in patients with cirrhosis or chronic liver disease. In recent …