Transcriptional regulation of secondary metabolite biosynthesis in plants
Plants produce thousands of secondary metabolites (aka specialized metabolites) of diverse
chemical nature. These compounds play important roles in protecting plants under adverse …
chemical nature. These compounds play important roles in protecting plants under adverse …
Taxol from Corylus avellana: paving the way for a new source of this anti-cancer drug
Taxol is amongst the most effective anti-cancer drugs available in market. The increasing
demand of this compound due to its use in treating wide range of cancers, as well as its high …
demand of this compound due to its use in treating wide range of cancers, as well as its high …
Engineering overexpression of ORCA3 and strictosidine glucosidase in Catharanthus roseus hairy roots increases alkaloid production
J Sun, CAM Peebles - Protoplasma, 2016 - Springer
Catharanthus roseus produces many pharmaceutically important terpenoid indole alkaloids
(TIAs) such as vinblastine, vincristine, ajmalicine, and serpentine. Past metabolic …
(TIAs) such as vinblastine, vincristine, ajmalicine, and serpentine. Past metabolic …
Recent advances on host plants and expression cassettes' structure and function in plant molecular pharming
A Makhzoum, R Benyammi, K Moustafa… - BioDrugs, 2014 - Springer
Plant molecular pharming is a promising system to produce important recombinant proteins
such as therapeutic antibodies, pharmaceuticals, enzymes, growth factors, and vaccines …
such as therapeutic antibodies, pharmaceuticals, enzymes, growth factors, and vaccines …
Discovery and metabolic engineering of iridoid/secoiridoid and monoterpenoid indole alkaloid biosynthesis
There has been remarkable progress in the discovery of specialized metabolism pathways
in the past few years. This has largely been due to the advent of inexpensive high …
in the past few years. This has largely been due to the advent of inexpensive high …
EASI Transformation: An Efficient Transient Expression Method for Analyzing Gene Function in Catharanthus roseus Seedlings
S Mortensen, D Bernal-Franco, LF Cole… - Frontiers in plant …, 2019 - frontiersin.org
The Catharanthus roseus plant is the exclusive source of the valuable anticancer terpenoid
indole alkaloids, vinblastine (VB) and vincristine (VC). The recent availability of …
indole alkaloids, vinblastine (VB) and vincristine (VC). The recent availability of …
Functional platform for controlled subcellular distribution of carbon nanotubes
As nanoparticles can cross different cellular barriers and access different tissues, control of
their uptake and cellular fate presents a functional approach that will be broadly applicable …
their uptake and cellular fate presents a functional approach that will be broadly applicable …
Efficient genetic transformation and regeneration system from hairy root of Origanum vulgare
Origanum vulgare L is commonly known as a wild marjoram and winter sweet which has
been used in the traditional medicine due to its therapeutic effects as stimulant, anticancer …
been used in the traditional medicine due to its therapeutic effects as stimulant, anticancer …
PbWoxT1 mRNA from pear (Pyrus betulaefolia) undergoes long‐distance transport assisted by a polypyrimidine tract binding protein
Little is known about the mechanisms by which mRNA s are transported over long distances
in the phloem between the rootstock and the scion in grafted woody plants. We identified an …
in the phloem between the rootstock and the scion in grafted woody plants. We identified an …
Screening and kinetic studies of catharanthine and ajmalicine accumulation and their correlation with growth biomass in Catharanthus roseus hairy roots
R Benyammi, C Paris, M Khelifi-Slaoui… - Pharmaceutical …, 2016 - Taylor & Francis
Abstract Context Catharanthus roseus (L.) G. Don (Apocynaceae) is still one of the most
important sources of t erpene indole alkaloids including anticancer and hypertensive drugs …
important sources of t erpene indole alkaloids including anticancer and hypertensive drugs …