Prevention, accurate diagnosis, and effective treatment of infections are the main challenges
in the overall management of infectious diseases. The best example is the ongoing SARs …

The tetrahydro-β-carboline (THBC) nucleus is a predominant feature of a vast array of
naturally occurring alkaloids. Most of these alkaloids have been found to exhibit significant …

A rhodium-catalyzed synthesis of indoloquinazolinone from a readily available hypervalent
iodonium reagent and N-carboxamide indole was developed. The protocol features broad …

Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …

A series of novel hybrids β-carboline-1, 3, 5-triazine were synthesized and evaluated for
their in vitro antileishmanial activity against promastigote and amastigote forms of …

A novel metal-free catalysis protocol for the synthesis of 1, 2-diarylpyrazolo [5, 1-b]
quinazolin-9 (1 H)-ones via intramolecular oxidative C–H amination of (E)-3-(arylamino)-2 …

In the present study, 45 maleimides have been synthesized and evaluated for anti-
leishmanial activities against L. donovani in vitro and cytotoxicity toward THP1 cells. All …

Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic
nucleus in the field of medicinal chemistry. It has different biological activities like …

Leishmaniasis is the most widespread pathogenic disease in several countries. Currently,
no effective vaccines are available, and the control of Leishmaniasis primarily relies on …

β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral …