Lignin, the richest source of renewable aromatics on the planet, is an intriguing raw material
for the construction of value-added aromatics. In the past decade, much progress has been …

Secondary metabolites obtained from natural sources are medicinally relevant molecules.
About one-third of all FDA-approved drugs are derived from or based on natural products …

Chagas disease (CD) is a neglected tropical disease endemic in 21 countries and affects
about 8 million people around the world. The pharmacotherapy for this disease is limited to …

Natural products have ancient history as fascinating sources of pharmaceuticals,
agrochemicals as well as NPs-derived drug/pesticide innovation. Its diversiform biological …

Aims From well-delimited immunomodulatory, redox and antimicrobial properties;
metronidazole and eugenol were used as structural platforms to assembly two new …

Endophytic fungi live inside vegetal tissues without causing damage to the host plant and
may provide lead compounds for drug discovery. The co-culture of two or more endophytic …

The Claisen–Schmidt condensation reaction of 3, 5-diacetyl-2, 6-dimethylpyridine with
salicylic aldehyde in the presence of an acid unexpectedly afforded 1-((5S, 11S)-2, 5 …

The protozoa, Trypanosoma cruzi (etiological agent of Chagas diseases–also named
American trypanosomiasis) and T. brucei (causative agent of human African …

Coumarins are widely distributed substances in plant species that promote phytotoxic
effects, allowing them to be exploited as herbicides less harmful to the environment, since …

Hundreds of millions of people worldwide are affected by Chagas' disease caused by
Trypanosoma cruzi. Since the current treatment lack efficacy, specificity, and suffers from …