Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing
A perfect bacterial genome assembly is one where the assembled sequence is an exact
match for the organism's genome—each replicon sequence is complete and contains no …
match for the organism's genome—each replicon sequence is complete and contains no …
Current uses and future perspectives of genomic technologies in clinical microbiology
I Bianconi, R Aschbacher, E Pagani - Antibiotics, 2023 - mdpi.com
Recent advancements in sequencing technology and data analytics have led to a
transformative era in pathogen detection and typing. These developments not only expedite …
transformative era in pathogen detection and typing. These developments not only expedite …
T2T-YAO: a telomere-to-telomere assembled diploid reference genome for Han Chinese
Y He, Y Chu, S Guo, J Hu, R Li, Y Zheng… - Genomics …, 2023 - academic.oup.com
Since its initial release in 2001, the human reference genome has undergone continuous
improvement in quality, and the recently released telomere-to-telomere (T2T) version—T2T …
improvement in quality, and the recently released telomere-to-telomere (T2T) version—T2T …
Oxford nanopore long-read sequencing enables the generation of complete bacterial and plasmid genomes without short-read sequencing
W Zhao, W Zeng, B Pang, M Luo, Y Peng, J Xu… - Frontiers in …, 2023 - frontiersin.org
Introduction Genome-based analysis is crucial in monitoring antibiotic-resistant bacteria
(ARB) and antibiotic-resistance genes (ARGs). Short-read sequencing is typically used to …
(ARB) and antibiotic-resistance genes (ARGs). Short-read sequencing is typically used to …
Antibiotic resistance: A key microbial survival mechanism that threatens public health
A Abbas, A Barkhouse, D Hackenberger, GD Wright - Cell Host & Microbe, 2024 - cell.com
Antibiotic resistance (AMR) is a global public health threat, challenging the effectiveness of
antibiotics in combating bacterial infections. AMR also represents one of the most crucial …
antibiotics in combating bacterial infections. AMR also represents one of the most crucial …
Do we still need Illumina sequencing data? Evaluating Oxford Nanopore Technologies R10. 4.1 flow cells and the Rapid v14 library prep kit for Gram negative …
N Lerminiaux, K Fakharuddin… - Canadian Journal of …, 2024 - cdnsciencepub.com
The best whole genome assemblies are currently built from a combination of highly accurate
short-read sequencing data and long-read sequencing data that can bridge repetitive and …
short-read sequencing data and long-read sequencing data that can bridge repetitive and …
From farm to fork: Persistence of clinically relevant multidrug-resistant and copper-tolerant klebsiella pneumoniae long after colistin withdrawal in poultry production
Concerns about colistin-resistant bacteria in animal food-environmental-human ecosystems
prompted the poultry sector to implement colistin restrictions and explore alternative trace …
prompted the poultry sector to implement colistin restrictions and explore alternative trace …
Detection of hidden antibiotic resistance through real-time genomics
E Sauerborn, NC Corredor, T Reska, A Perlas… - Nature …, 2024 - nature.com
Real-time genomics through nanopore sequencing holds the promise of fast antibiotic
resistance prediction directly in the clinical setting. However, concerns about the accuracy of …
resistance prediction directly in the clinical setting. However, concerns about the accuracy of …
Do we still need Illumina sequencing data?: Evaluating Oxford Nanopore Technologies R10. 4.1 flow cells and v14 library prep kits for Gram negative bacteria whole …
N Lerminiaux, K Fakharuddin, MR Mulvey, L Mataseje - biorxiv, 2023 - biorxiv.org
The best whole genome assemblies are currently built from a combination of highly accurate
short-read sequencing data and long-read sequencing data that can bridge repetitive and …
short-read sequencing data and long-read sequencing data that can bridge repetitive and …
Genomic diversity and antimicrobial resistance in clinical Klebsiella pneumoniae isolates from tertiary hospitals in Southern Ghana
Objectives Comprehensive data on the genomic epidemiology of hospital-associated
Klebsiella pneumoniae in Ghana are scarce. This study investigated the genomic diversity …
Klebsiella pneumoniae in Ghana are scarce. This study investigated the genomic diversity …