Publisher Summary This chapter describes the effect of antibody on virus-infected cells with
special reference to the human system. The destruction by antibody of the infected cells …

IL-12 has been shown to enhance cellular immunity in vitro and in vivo. Recent reports have
suggested that combining DNA vaccine approach with immune stimulatory molecules …

Antibody-dependent cellular cytotoxicity (ADCC) to cells infected with herpes simplex virus
(HSV) is a mechanism of destruction of these cells by a combination of antiviral antibody and …

SEVERAL permanent murine macrophage-like cell lines exhibiting various macrophage-
associated effector functions have been described1–3, but establishment of permanent …

The role of antiviral antibodies in protection against neonatal herpes simplex virus (HSV)
infection remains controversial. The relationship between neonatal and maternal antiHSV …

Investigations of polymorphonuclear leukocyte (PMN) function were performed in a 5-yr-old
white female with delayed umbilical cord separation, impaired pus formation, and a severe …

Several vaccines have been investigated experimentally in the herpes simplex virus type 2
(HSV-2) model system. While it is believed that CD4+-T-cell responses are important for …

Two abortifacient proteins, α-and β-momorcharin, have been purified from the seeds of the
bitter melon (Momordica charantia). It was found that non-cytotoxic concentrations of these …

FcγRs are critical mediators of mAb cancer therapies, because they drive cytotoxic
processes upon binding of effector cells to opsonized targets. Along with NK cells …

Summary HIV-1 envelope (Env) conformation determines the susceptibility of infected CD4+
T cells to antibody-dependent cellular cytotoxicity (ADCC). Upon interaction with CD4, Env …