[HTML][HTML] Sustained proliferation in cancer: Mechanisms and novel therapeutic targets

MA Feitelson, A Arzumanyan, RJ Kulathinal… - Seminars in cancer …, 2015 - Elsevier
Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

Bioactivities of phytochemicals present in tomato

P Chaudhary, A Sharma, B Singh… - Journal of food science and …, 2018 - Springer
Tomato is a wonder fruit fortified with health-promoting phytochemicals that are beneficial in
preventing important chronic degenerative disorders. Tomato is a good source of phenolic …

Cancer chemoprevention by caroteno

T Tanaka, M Shnimizu, H Moriwaki - Molecules, 2012 - mdpi.com
Carotenoids are natural fat-soluble pigments that provide bright coloration to plants and
animals. Dietary intake of carotenoids is inversely associated with the risk of a variety of …

Mechanistic aspects of carotenoid health benefits–where are we now?

T Bohn, ML Bonet, P Borel, J Keijer… - Nutrition Research …, 2021 - cambridge.org
Dietary intake and tissue levels of carotenoids have been associated with a reduced risk of
several chronic diseases, including cardiovascular diseases, type 2 diabetes, obesity, brain …

New insights into molecular mechanism behind anti-cancer activities of lycopene

BP Puah, J Jalil, A Attiq, Y Kamisah - Molecules, 2021 - mdpi.com
Lycopene is a well-known compound found commonly in tomatoes which brings wide range
of health benefits against cardiovascular diseases and cancers. From an anti-cancer …

[HTML][HTML] Terpenoids as potential chemopreventive and therapeutic agents in liver cancer

RJ Thoppil, A Bishayee - World journal of hepatology, 2011 - ncbi.nlm.nih.gov
Despite significant advances in medicine, liver cancer, predominantly hepatocellular
carcinoma remains a major cause of death in the United States as well as the rest of the …

Clinical evidence of the benefits of phytonutrients in human healthcare

N Monjotin, MJ Amiot, J Fleurentin, JM Morel, S Raynal - Nutrients, 2022 - mdpi.com
Phytonutrients comprise many different chemicals, including carotenoids, indoles,
glucosinolates, organosulfur compounds, phytosterols, polyphenols, and saponins. This …

Antioxidant and anti-proliferative properties of lycopene

M Kelkel, M Schumacher, M Dicato… - Free radical …, 2011 - Taylor & Francis
The recent search for new anti-cancer drugs focuses more on natural compounds from the
regular human diet because these compounds rarely exhibit severe side-effects yet …

Multitargeted therapy of cancer by lycopene

RB Van Breemen, N Pajkovic - Cancer letters, 2008 - Elsevier
Lycopene (ψ, ψ-carotene) is the most abundant carotenoid in tomatoes and is the red
pigment of not only tomatoes but also rosehips, watermelon, papaya, pink grapefruit, and …

Cellular signaling perturbation by natural products

FH Sarkar, Y Li, Z Wang, D Kong - Cellular signalling, 2009 - Elsevier
Cancer cells are known to have alterations in multiple cellular signaling pathways and
because of the complexities in the communication between multiple signaling networks, the …