The role of oxygen transport in atherosclerosis and vascular disease
Atherosclerosis and vascular disease of larger arteries are often associated with hypoxia
within the layers of the vascular wall. In this review, we begin with a brief overview of the …
within the layers of the vascular wall. In this review, we begin with a brief overview of the …
Mathematical modelling and simulation of atherosclerosis formation and progress: a review
NA Avgerinos, P Neofytou - Annals of Biomedical Engineering, 2019 - Springer
Cardiovascular disease (CVD) is a major threat to human health since it is the leading cause
of death in western countries. Atherosclerosis is a type of CVD related to hypertension …
of death in western countries. Atherosclerosis is a type of CVD related to hypertension …
MicroRNA-19a mediates the suppressive effect of laminar flow on cyclin D1 expression in human umbilical vein endothelial cells
Endothelial cells (ECs) respond to changes in mechanical forces, leading to the modulation
of signaling networks and cell function; an example is the inhibition of EC proliferation by …
of signaling networks and cell function; an example is the inhibition of EC proliferation by …
Mathematical modelling of atheroma plaque formation and development in coronary arteries
Atherosclerosis is a vascular disease caused by inflammation of the arterial wall, which
results in the accumulation of low-density lipoprotein (LDL) cholesterol, monocytes …
results in the accumulation of low-density lipoprotein (LDL) cholesterol, monocytes …
The story of wall shear stress in coronary artery atherosclerosis: biochemical transport and mechanotransduction
M Mahmoudi, A Farghadan… - Journal of …, 2021 - asmedigitalcollection.asme.org
Coronary artery atherosclerosis is a local, multifactorial, complex disease, and the leading
cause of death in the US. Complex interactions between biochemical transport and …
cause of death in the US. Complex interactions between biochemical transport and …
Patient-specific three-dimensional simulation of LDL accumulation in a human left coronary artery in its healthy and atherosclerotic states
We calculate low-density lipoprotein (LDL) transport from blood into arterial walls in a three-
dimensional, patient-specific model of a human left coronary artery. The in vivo anatomy …
dimensional, patient-specific model of a human left coronary artery. The in vivo anatomy …
Modeling of the early stage of atherosclerosis with emphasis on the regulation of the endothelial permeability
T Silva, W Jäger, M Neuss-Radu, A Sequeira - Journal of Theoretical …, 2020 - Elsevier
In this paper, we develop a mathematical model for the early stage of atherosclerosis, as a
chronic inflammatory disease. It includes also processes that are relevant for the” thickening” …
chronic inflammatory disease. It includes also processes that are relevant for the” thickening” …
Simulation of atherosclerotic plaque growth using computational biomechanics and patient-specific data
Atherosclerosis is the one of the major causes of mortality worldwide, urging the need for
prevention strategies. In this work, a novel computational model is developed, which is used …
prevention strategies. In this work, a novel computational model is developed, which is used …
Simulation of a pulsatile non-Newtonian flow past a stenosed 2D artery with atherosclerosis
Atherosclerotic plaque can cause severe stenosis in the artery lumen. Blood flow through a
substantially narrowed artery may have different flow characteristics and produce different …
substantially narrowed artery may have different flow characteristics and produce different …
Computational modelling of atherosclerosis
A Parton, V McGilligan, M O'Kane… - Briefings in …, 2016 - academic.oup.com
Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood
cholesterol a significant risk factor. The World Health Organization estimates that …
cholesterol a significant risk factor. The World Health Organization estimates that …