Spheroid culture system methods and applications for mesenchymal stem cells

NE Ryu, SH Lee, H Park - Cells, 2019 - mdpi.com
Owing to the importance of stem cell culture systems in clinical applications, researchers
have extensively studied them to optimize the culture conditions and increase efficiency of …

[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Microfluidic organ/body-on-a-chip devices at the convergence of biology and microengineering

AR Perestrelo, ACP Águas, A Rainer, G Forte - Sensors, 2015 - mdpi.com
Recent advances in biomedical technologies are mostly related to the convergence of
biology with microengineering. For instance, microfluidic devices are now commonly found …

Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells

A Afshari, S Shamdani, G Uzan, S Naserian… - Stem cell research & …, 2020 - Springer
Due to the prominent role of the liver in the body and detoxification, its functionality can be
affected in an irreversible manner by diseases. This phenomenon renders the liver to stop …

[HTML][HTML] Microfluidic devices for cell cultivation and proliferation

M Tehranirokh, AZ Kouzani, PS Francis, JR Kanwar - Biomicrofluidics, 2013 - pubs.aip.org
Microfluidic technology provides precise, controlled-environment, cost-effective, compact,
integrated, and high-throughput microsystems that are promising substitutes for …

Historical perspectives and advances in mesenchymal stem cell research for the treatment of liver diseases

CW Lee, YF Chen, HH Wu, OK Lee - Gastroenterology, 2018 - Elsevier
Liver transplantation is the only effective therapy for patients with decompensated cirrhosis
and fulminant liver failure. However, due to a shortage of donor livers and complications …

Lab-on-a-chip devices as an emerging platform for stem cell biology

K Gupta, DH Kim, D Ellison, C Smith, A Kundu, J Tuan… - Lab on a Chip, 2010 - pubs.rsc.org
The advent of stem cell based therapies has brought regenerative medicine into an
increased focus as a part of the modern medicine practice, with a potential to treat a myriad …

Controlling differentiation of stem cells for developing personalized organ‐on‐chip platforms

A Geraili, P Jafari, MS Hassani… - Advanced …, 2018 - Wiley Online Library
Abstract Organ‐on‐chip (OOC) platforms have attracted attentions of pharmaceutical
companies as powerful tools for screening of existing drugs and development of new drug …

Biochemical and molecular characterization of hepatocyte‐like cells derived from human bone marrow mesenchymal stem cells on a novel three‐dimensional …

S Kazemnejad, A Allameh, M Soleimani… - Journal of …, 2009 - Wiley Online Library
Background: There is significant interest in using nanofibers in tissue engineering from stem
cells. The transdifferentiation of mesenchymal stem cells into the hepatic lineage in a …

Regeneration-on-a-chip? The perspectives on use of microfluidics in regenerative medicine

B Harink, S Le Gac, R Truckenmüller… - Lab on a Chip, 2013 - pubs.rsc.org
The aim of regenerative medicine is to restore or establish normal function of damaged
tissues or organs. Tremendous efforts are placed into development of novel regenerative …