Arsenic is a hazardous heavy metalloid that imposes threats to human health globally. It is
widely spread throughout the environment in various forms. Arsenic-based compounds are …

Dimethylmonothioarsinic acid (DMMTA V), a pentavalent thio-arsenic derivative, has been
found in bodily fluids and tissues including urine, liver, kidney homogenates, plasma, and …

The success of arsenic trioxide (ATO) in acute promyelocytic leukemia has driven a plethora
studies to investigate its efficacy in other malignancies. However, the inherent toxicity of ATO …

The detoxification of quinones through NAD (P) H: quinone oxidoreductase (NQO1) is a
crucial mechanism to maintain cellular homeostasis. The exposure to heavy metals …

The aryl hydrocarbon receptor (AhR) functions as a vital ligand-activated transcription factor,
governing both physiological and pathophysiological processes. Notably, it responds to …

Abstract Methylmercury (MeHg) and 2, 3, 7, 8-tetrachlorodibenzodioxin (TCDD) are potent
environmental pollutants implicated in the modulation of xenobiotic-metabolizing enzymes …

Ponatinib and tofacitinib, established kinase inhibitors and FDA-approved for chronic
myeloid leukemia and rheumatoid arthritis, are recently undergoing investigation in diverse …

Triazole compounds (1a–3a) and their oxime derivatives (1b–3b) were synthesized. The
structures of these synthesized compounds were characterized using common …

The human aryl hydrocarbon receptor (AhR), a ligand‐dependent transcription factor, plays
a pivotal role in a diverse array of pathways in biological and pathophysiological events …