Cells have the ability to respond to various types of environmental cues, and in many cases
these cues induce directed cell migration towards or away from these signals. How cells …

Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …

INTRODUCTION The collective behavior of cells and insects often relies on self-organizing
processes. By releasing attractant signals, a few individuals can initiate the accumulation …

Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …

Neutrophils play a critical role in the host defense against bacterial and fungal infections, but
their inappropriate activation also contributes to tissue damage during autoimmune and …

Neutrophils are the primary cells recruited to inflamed sites during an innate immune
response to tissue damage and/or infection. They are finely sensitive to inciting stimuli to …

Neutrophils have long been viewed as short-lived cells crucial for the elimination of
extracellular pathogens, possessing a limited role in the orchestration of the immune …

Chemotaxis, or directed migration of cells along a chemical gradient, is a highly coordinated
process that involves gradient sensing, motility, and polarity. Most of our understanding of …

CD177 is a glycosylphosphatidylinositol (GPI)-anchored protein expressed by a variable
proportion of human neutrophils that mediates surface expression of the antineutrophil …

Neutrophil migration to sites of inflammation and the subsequent execution of multiple
functions are designed to contain and kill invading pathogens. These highly regulated and …