Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugs

PN Patsalos, E Perucca - The Lancet Neurology, 2003 - thelancet.com
Antiepileptic drugs (AEDs) are commonly prescribed for long periods, up to a lifetime, and
many patients will require treatment with other agents for the management of concomitant or …

Clinically significant pharmacokinetic drug interactions with carbamazepine: an update

E Spina, F Pisani, E Perucca - Clinical pharmacokinetics, 1996 - Springer
Carbamazepine is one of the most commonly prescribed antiepileptic drugs and is also
used in the treatment of trigeminal neuralgia and psychiatric disorders, particularly bipolar …

Depression in epilepsy: etiology, phenomenology, and treatment

MV Lambert, MM Robertson - Epilepsia, 1999 - Wiley Online Library
A history of depression or depressive symptomatology has been reported in up to two‐thirds
of patients with medically intractable epilepsy, whereas community studies have …

Viloxazine in the management of CNS disorders: a historical overview and current status

RL Findling, SA Candler, AF Nasser, S Schwabe, C Yu… - CNS drugs, 2021 - Springer
Viloxazine has a long history of clinical use in Europe as an antidepressant, and has
recently been repurposed into an extended-release form for the treatment of attention …

Clinical significance of pharmacokinetic interactions between antiepileptic and psychotropic drugs

E Spina, E Perucca - Epilepsia, 2002 - Wiley Online Library
As antiepileptic drugs (AEDs) and psychotropic agents are increasingly used in
combination, the possibility of pharmacokinetic interactions between these compounds is …

Drug interactions that matter: a critical reappraisal

GT McInnes, MJ Brodie - Drugs, 1988 - Springer
Drug interactions are ubiquitous but those with proven clinical relevance are much less
common. Only when the combined effects of the interacting drugs are greater or less than …

Antiepileptic drugs: a review of clinically significant drug interactions

PN Patsalos, JS Duncan - Drug Safety, 1993 - Springer
Approximately 20 to 30% of patients with active intractable epilepsy are commonly treated
with polytherapy antiepileptic drug regimens, and these patients may experience …

Oxcarbazepine: pharmacokinetic interactions and their clinical relevance

A Baruzzi, F Albani, R Riva - Epilepsia, 1994 - Wiley Online Library
Antiepileptic drug (AED) interactions are a common problem during epilepsy treatment.
Oxcarbazepine (OCBZ) is a keto homologue of carbamazepine (CBZ) with a completely …

[PDF][PDF] Mood disorders in patients with epilepsy

M Dudra-Jastrzêbska, MM Andres-Mach… - Pharmacological …, 2007 - if-pan.krakow.pl
Epilepsy is a common disabling neurological disorder associated with increased rates of
mood disorders especially depression as compared to the general population. Most …

Clinically significant drug–drug interactions with agents for attention-deficit/hyperactivity disorder

G Schoretsanitis, J de Leon, CB Eap, JM Kane… - CNS drugs, 2019 - Springer
This article provides an overview of the pharmacokinetic drug–drug interactions (DDIs) for
agents prescribed for attention-deficit/hyperactivity disorder (ADHD). Polypharmacy in the …