While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …

Aging and various age-related diseases are associated with reductions in melatonin
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …

Plants containing resveratrol have been used effectively in traditional medicine for over
2000 years. It can be found in some plants, fruits, and derivatives, such as red wine …

Alzheimer's disease (AD) is an age-related neurodegenerative disease with multiple
predisposing factors and complicated pathogenesis. Aβ peptide is one of the most important …

Myocardial contractile dysfunction is associated with an increase in mitochondrial fission in
patients with diabetes. However, whether mitochondrial fission directly promotes diabetes …

Abstract Resveratrol (3, 5, 4′‐trihydroxystilbene) is a nonflavonoid polyphenol that
naturally occurs as phytoalexin. It is produced by plant sources such as grapes, apples …

Sirtuins are a class of NAD+-dependent deacetylases having beneficial health effects. This
extensive review describes the numerous intracellular actions of the seven mammalian …

Currently the human population is aging faster. This leads to higher dependency rates and
the transformation of health and social care to adapt to this aged population. Among the …

The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …