Endometriosis and nuclear receptors

BD Yilmaz, SE Bulun - Human reproduction update, 2019 - academic.oup.com
BACKGROUND Endometriosis is recognized as a steroid-dependent disorder; however, the
precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling …

Endometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis

FM Reis, F Petraglia, RN Taylor - Human reproduction update, 2013 - academic.oup.com
BACKGROUND The recruitment of immune cells by chemokines and the regulation of
endometrial cell apoptosis are critical aspects of endometriosis biology. Here, we review the …

Progesterone receptor ligands for the treatment of endometriosis: the mechanisms behind therapeutic success and failure

FM Reis, LM Coutinho, S Vannuccini… - Human …, 2020 - academic.oup.com
BACKGROUND Despite intense research, it remains intriguing why hormonal therapies in
general and progestins in particular sometimes fail in endometriosis. OBJECTIVE AND …

[HTML][HTML] Endometriosis: Perspective, lights, and shadows of etiology

S Asghari, A Valizadeh, L Aghebati-Maleki… - Biomedicine & …, 2018 - Elsevier
Endometriosis refers to the growth of ectopic endometrial tissue outside the uterine cavity.
About 10–15% of female in reproductive age suffer from endometriosis. Several etiologies …

Polymorphisms and endometriosis: a systematic review and meta-analyses

L Méar, M Herr, A Fauconnier, C Pineau… - Human reproduction …, 2020 - academic.oup.com
BACKGROUND Endometriosis is an estrogen-dependent gynecological disorder that affects
at least 10% of women of reproductive age. It may lead to infertility and non-specific …

Functional genetic polymorphisms and female reproductive disorders: part II—endometriosis

CB Tempfer, M Simoni, B Destenaves… - Human reproduction …, 2009 - academic.oup.com
BACKGROUND Endometriosis has a strong genetic component, and numerous genetic
studies have been reported. METHODS We have systematically reviewed these studies and …

Genetic characterization of endometriosis patients: review of the literature and a prospective cohort study on a Mediterranean population

S Angioni, MN D'Alterio, A Coiana, F Anni… - International journal of …, 2020 - mdpi.com
The pathogenesis of endometriosis is unknown, but some evidence supports a genetic
predisposition. The purpose of this study was to evaluate the recent literature on the genetic …

Understanding the role of epigenomic, genomic and genetic alterations in the development of endometriosis

H Kobayashi, S Imanaka… - Molecular medicine …, 2014 - spandidos-publications.com
Endometriosis is a complex disease influenced by genetic, epigenetic and environmental
factors. The aim of the present study was to describe genomic instability, genetic …

Genetics of endometriosis: a comprehensive review

D Deiana, S Gessa, M Anardu, A Daniilidis… - Gynecological …, 2019 - Taylor & Francis
This review aimed to critically evaluate the review, observational, cohort, and case–control
studies performed so far in order to assess the association between endometriosis and …

[PDF][PDF] The effect of hormones on endometriosis development

CP Barbosa, AMB De Souza, B Bianco… - Minerva …, 2011 - researchgate.net
Vol. 63-No. 4 MINERVA GINECOLOGICA 375 a putative role for ubiquitous environmental
contaminants in the occurrence of endometriosis. Here, we reviewed significant articles …