Fatty acid-binding protein 4 in cardiovascular and metabolic diseases

M Furuhashi - Journal of atherosclerosis and thrombosis, 2019 - jstage.jst.go.jp
Fatty acid trafficking in cells affects many aspects of cellular function3). Fatty acids act both
as an energy source and as signals for metabolic regulations including gene expression …

DOCK 6: Impact of new features and current docking performance

WJ Allen, TE Balius, S Mukherjee… - Journal of …, 2015 - Wiley Online Library
This manuscript presents the latest algorithmic and methodological developments to the
structure‐based design program DOCK 6.7 focused on an updated internal energy function …

Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages

Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …

Fatty acid-binding proteins (FABPs) are intracellular carriers for Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD)

MW Elmes, M Kaczocha, WT Berger, KN Leung… - Journal of Biological …, 2015 - ASBMB
Δ 9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana
(Cannabis) and may be formulated, individually or in combination in pharmaceuticals such …

Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue

W Chen, J Dong, L Plate, DE Mortenson… - Journal of the …, 2016 - ACS Publications
Arylfluorosulfates have appeared only rarely in the literature and have not been explored as
probes for covalent conjugation to proteins, possibly because they were assumed to …

Diverse roles of fatty acid binding proteins (FABPs) in development and pathogenesis of cancers

M Amiri, S Yousefnia, FS Forootan, M Peymani… - Gene, 2018 - Elsevier
One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Fatty acid binding proteins: tissue-specific functions in health and disease

AE Thumser, JB Moore, NJ Plant - Current Opinion in Clinical …, 2014 - journals.lww.com
Fatty acid binding proteins: tissue-specific functions in he... : Current Opinion in Clinical
Nutrition & Metabolic Care Fatty acid binding proteins: tissue-specific functions in health and …

Tandem catalysis for asymmetric coupling of ethylene and enynes to functionalized cyclobutanes

VV Pagar, TV RajanBabu - Science, 2018 - science.org
Transformation of simple precursors into structurally complex cyclobutanes, present in many
biologically important natural products and pharmaceuticals, is of considerable interest in …

Enhanced endocannabinoid tone as a potential target of pharmacotherapy

M Toczek, B Malinowska - Life sciences, 2018 - Elsevier
The endocannabinoid system is up-regulated in numerous pathophysiological states such
as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular …

Transport of endocannabinoids across the plasma membrane and within the cell

CJ Fowler - The FEBS journal, 2013 - Wiley Online Library
Endocannabinoids are readily accumulated from the extracellular space by cells. Although
their uptake properties have the appearance of a process of facilitated diffusion, it is by no …