This manuscript presents the latest algorithmic and methodological developments to the structure‐based design program DOCK 6.7 focused on an updated internal energy function …
Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao… - Nature …, 2021 - nature.com
Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S- glutathionylation plays an important role in cellular antioxidant defense. Here we report that …
Δ 9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) occur naturally in marijuana (Cannabis) and may be formulated, individually or in combination in pharmaceuticals such …
W Chen, J Dong, L Plate, DE Mortenson… - Journal of the …, 2016 - ACS Publications
Arylfluorosulfates have appeared only rarely in the literature and have not been explored as probes for covalent conjugation to proteins, possibly because they were assumed to …
One of the most importantly involved pathways in cancer development is fatty-acid signaling pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …
AE Thumser, JB Moore, NJ Plant - Current Opinion in Clinical …, 2014 - journals.lww.com
Fatty acid binding proteins: tissue-specific functions in he... : Current Opinion in Clinical Nutrition & Metabolic Care Fatty acid binding proteins: tissue-specific functions in health and …
Transformation of simple precursors into structurally complex cyclobutanes, present in many biologically important natural products and pharmaceuticals, is of considerable interest in …
M Toczek, B Malinowska - Life sciences, 2018 - Elsevier
The endocannabinoid system is up-regulated in numerous pathophysiological states such as inflammatory, neurodegenerative, gastrointestinal, metabolic and cardiovascular …
CJ Fowler - The FEBS journal, 2013 - Wiley Online Library
Endocannabinoids are readily accumulated from the extracellular space by cells. Although their uptake properties have the appearance of a process of facilitated diffusion, it is by no …