The Th17/IL-17 axis and kidney diseases, with focus on lupus nephritis

FC Paquissi, H Abensur - Frontiers in Medicine, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a disease characterized by dysregulation and
hyperreactivity of the immune response at various levels, including hyperactivation of …

Autoimmune rheumatic diseases and vascular function: the concept of autoimmune atherosclerosis

AM Hedar, MH Stradner, A Roessler… - Journal of clinical …, 2021 - mdpi.com
Autoimmune rheumatic diseases (AIRDs) with unknown etiology are increasing in incidence
and prevalence. Up to 5% of the population is affected. AIRDs include rheumatoid arthritis …

Targeting the gut microbiota with dietary fibers: a novel approach to prevent the development cardiovascular complications linked to systemic lupus erythematosus in …

J Moleón, C González-Correa, I Robles-Vera… - Gut …, 2023 - Taylor & Francis
This study is to investigate whether dietary fiber intake prevents vascular and renal damage
in a genetic mouse model of systemic lupus erythematosus (SLE), and the contribution of gut …

Hypertension as a cardiovascular risk factor in autoimmune rheumatic diseases

E Bartoloni, A Alunno, R Gerli - Nature Reviews Cardiology, 2018 - nature.com
Evidence for the increased risk of cardiovascular morbidity and mortality in patients with
chronic inflammatory and systemic autoimmune diseases has accumulated during the past …

The use of cyclosporine A in rheumatology: a 2016 comprehensive review

CB Chighizola, VH Ong, PL Meroni - Clinical reviews in allergy & …, 2017 - Springer
Cyclosporine A, an inhibitor of calcineurin, exerts an immunomodulator action interfering
with T cell activation. Even though novel therapeutic tools have emerged, CyA still …

Autoimmune disease-associated hypertension

VL Wolf, MJ Ryan - Current hypertension reports, 2019 - Springer
Abstract Purpose of Review To highlight important new findings on the topic of autoimmune
disease-associated hypertension. Recent Findings Autoimmune diseases including …

Metabolic syndrome and systemic lupus erythematosus: the connection

CC Mok - Expert Review of Clinical Immunology, 2019 - Taylor & Francis
ABSTRACT Introduction: The metabolic syndrome (MetS) is now recognized as a chronic
proinflammatory and prothrombotic state that aggravates insulin resistance, oxidative injury …

Gut microbiota contributes to the development of hypertension in a genetic mouse model of systemic lupus erythematosus

N de la Visitacion, I Robles‐Vera… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Hypertension is an important cardiovascular risk factor that is
prevalent in the systemic lupus erythematosus patient population. Here, we have …

Plasma cell depletion attenuates hypertension in an experimental model of autoimmune disease

EB Taylor, MT Barati, DW Powell, HR Turbeville… - …, 2018 - Am Heart Assoc
Numerous studies show a direct relation between circulating autoantibodies, characteristic
of systemic autoimmune disorders, and primary hypertension in humans. Whether these …

Understanding mechanisms of hypertension in systemic lupus erythematosus

EB Taylor, MJ Ryan - Therapeutic advances in …, 2017 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that predominately
affects women of reproductive age. Hypertension is an important cardiovascular risk factor …