Neuro-orchestration of sleep and wakefulness

BA Sulaman, S Wang, J Tyan… - Nature neuroscience, 2023 - nature.com
Although considered an inactive state for centuries, sleep entails many active processes
occurring at the cellular, circuit and organismal levels. Over the last decade, several key …

[HTML][HTML] Cellular mechanisms of conscious processing

J Aru, M Suzuki, ME Larkum - Trends in cognitive sciences, 2020 - cell.com
Recent breakthroughs in neurobiology indicate that the time is ripe to understand how
cellular-level mechanisms are related to conscious experience. Here, we highlight the …

[HTML][HTML] The spatial and cell-type distribution of SARS-CoV-2 receptor ACE2 in the human and mouse brains

R Chen, K Wang, J Yu, D Howard, L French… - Frontiers in …, 2021 - frontiersin.org
By engaging angiotensin-converting enzyme 2 (ACE2 or Ace2), the novel pathogenic
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades host cells and …

Thalamic subnetworks as units of function

DS Roy, Y Zhang, MM Halassa, G Feng - Nature neuroscience, 2022 - nature.com
The thalamus engages in various functions including sensory processing, attention, decision
making and memory. Classically, this diversity of function has been attributed to the nuclear …

Specific electromagnetic radiation in the wireless signal range increases wakefulness in mice

L Liu, H Deng, X Tang, Y Lu, J Zhou… - Proceedings of the …, 2021 - National Acad Sciences
Electromagnetic radiation (EMR) in the environment has increased sharply in recent
decades. The effect of environmental EMR on living organisms remains poorly …

The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

A specific circuit in the midbrain detects stress and induces restorative sleep

X Yu, G Zhao, D Wang, S Wang, R Li, A Li, H Wang… - Science, 2022 - science.org
In mice, social defeat stress (SDS), an ethological model for psychosocial stress, induces
sleep. Such sleep could enable resilience, but how stress promotes sleep is unclear. Activity …

GABA and glutamate neurons in the VTA regulate sleep and wakefulness

X Yu, W Li, Y Ma, K Tossell, JJ Harris, EC Harding… - Nature …, 2019 - nature.com
We screened for novel circuits in the mouse brain that promote wakefulness. Chemogenetic
activation experiments and electroencephalogram recordings pointed to …

[HTML][HTML] The paraventricular nucleus of the thalamus as an integrating and relay node in the brain anxiety network

GJ Kirouac - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
The brain anxiety network is composed of a number of interconnected cortical regions that
detect threats and execute appropriate defensive responses via projections to the shell of …

Understanding the neural mechanisms of general anesthesia from interaction with sleep–wake state: a decade of discovery

WW Bao, S Jiang, WM Qu, WX Li, CH Miao… - Pharmacological …, 2023 - ASPET
The development of cutting-edge techniques to study specific brain regions and neural
circuits that regulate sleep–wake brain states and general anesthesia (GA), has increased …