Heart disease is a leading cause of death with unmet clinical needs for targeted treatment
options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine …

Introduction: Tumor necrosis factor (TNF) receptor 2 (TNFR2) is one of two receptors of the
cytokines, TNF and lymphotoxin-α. TNFR1 is a strong inducer of proinflammatory activities …

Abstract Background Endothelial progenitor cells (EPCs) are non-differentiated endothelial
cells (ECs) present in blood circulation that are involved in neo-vascularization and …

MicroRNAs play a crucial role in regulating the immune responses induced by
ischemia/reperfusion injury. Through their ability to modulate gene expression, microRNAs …

Since adult stem cells are responsible for replenishing tissues throughout life, it is vital to
understand how failure to undergo apoptosis can dictate stem cell behavior both intrinsically …

Many cytokines are currently under investigation as potential target to improve cardiac
function and outcome in the setting of acute myocardial infarction (MI) or chronic heart failure …

Tumor necrosis factor-α (TNF-α) contributes to myocardial infarction (MI) injury.
Polymorphism of TNF-α gene promoter region and secretion and release of TNF-α and its …

Tumor necrosis factor alpha (TNFα) is a potent inhibitor of neurogenesis in vitro but here we
show that TNFα signaling has both positive and negative effects on neurogenesis in vivo …

Objective—Evidence suggests that chronic low-grade inflammation and oxidative stress are
related to cardiovascular disease (CVD) and mortality. Approach and Results—We …

Background Bone marrow derived endothelial progenitor cells (EPCs) are immature
endothelial cells (ECs) involved in neo-angiogenesis and endothelial homeostasis and are …