Anatomical and physiological alterations of pregnancy

JM Kazma, J van den Anker, K Allegaert… - … of pharmacokinetics and …, 2020 - Springer
The extensive metabolic demands of pregnancy require specific physiological and
anatomical changes. These changes affect almost all organ systems, including the …

Pulmonary thrombo-embolism in pregnancy: diagnosis and management

LE Simcox, L Ormesher, C Tower, IA Greer - Breathe, 2015 - Eur Respiratory Soc
Key points Venous thromboembolism (VTE) in pregnancy remains a leading cause of direct
maternal mortality in the developed world and identifiable risk factors are increasing in …

Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC/ESRA guidelines

S Kietaibl, R Ferrandis, A Godier, J Llau… - European Journal of …, 2022 - journals.lww.com
BACKGROUND Bleeding is a potential complication after neuraxial and peripheral nerve
blocks. The risk is increased in patients on antiplatelet and anticoagulant drugs. This joint …

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an …

IM Bistervels, A Buchmüller, HMG Wiegers, FN Áinle… - The Lancet, 2022 - thelancet.com
Background Pregnancy-related venous thromboembolism is a leading cause of maternal
morbidity and mortality, and thromboprophylaxis is indicated in pregnant and post-partum …

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

SM Bates, S Middeldorp, M Rodger, AH James… - Journal of thrombosis …, 2016 - Springer
Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep
vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention …

The Society for Obstetric Anesthesia and Perinatology consensus statement on the anesthetic management of pregnant and postpartum women receiving …

L Leffert, A Butwick, B Carvalho, K Arendt… - Anesthesia & …, 2018 - journals.lww.com
Venous thromboembolism is recognized as a leading cause of maternal death in the United
States. Thromboprophylaxis has been highlighted as a key preventive measure to reduce …

Anticoagulation during pregnancy: evolving strategies with a focus on mechanical valves

L Alshawabkeh, KE Economy, AM Valente - Journal of the American …, 2016 - jacc.org
Pregnancy is associated with a hypercoagulable state. Women requiring anticoagulation
need careful attention throughout pregnancy and the post-partum period. The choice of …

Pregnancy complicated by venous thrombosis

IA Greer - New England Journal of Medicine, 2015 - Mass Medical Soc
Key Clinical Points Venous Thrombosis in Pregnancy Venous thromboembolism is a
leading cause of maternal mortality and morbidity in the developed world. The risk of deep …

Treatment of pregnancy-associated venous thromboembolism–position paper from the working Group in Women's health of the Society of Thrombosis and …

A Gerhardt, B Toth, R Bauersachs - Vasa, 2016 - econtent.hogrefe.com
Venous thromboembolism (VTE) is a major cause of maternal morbidity during pregnancy
and the postpartum period. However, because there is a lack of adequate study data …

[HTML][HTML] Fixed dose rivaroxaban can be used in extremes of bodyweight: a population pharmacokinetic analysis

V Speed, B Green, LN Roberts, S Woolcombe… - Journal of Thrombosis …, 2020 - Elsevier
Background Emerging safety and efficacy data for rivaroxaban suggest traditional therapy
and rivaroxaban are comparable in the morbidly obese. However, real‐world data that …