[HTML][HTML] Natural and synthetic nanovectors for cancer therapy

A Eftekhari, C Kryschi, D Pamies, S Gulec… - …, 2023 - ncbi.nlm.nih.gov
Nanomaterials have been extensively studied in cancer therapy as vectors that may improve
drug delivery. Such vectors not only bring numerous advantages such as stability …

Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing

A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Exosomes produced by mesenchymal stem cells drive differentiation of myeloid cells into immunosuppressive M2-polarized macrophages in breast cancer

S Biswas, G Mandal, S Roy Chowdhury… - The Journal of …, 2019 - journals.aai.org
Concepts and design of the project were done by SB, GM, SRC, KKP, JRC-G., and ABSB,
GM, SP, and CA performed the experiments. The analysis of the data was conducted by SB …

MSC‐derived exosomes‐based therapy for peripheral nerve injury: a novel therapeutic strategy

R Dong, Y Liu, Y Yang, H Wang, Y Xu… - BioMed research …, 2019 - Wiley Online Library
Although significant advances have been made in synthetic nerve conduits and surgical
techniques, complete regeneration following peripheral nerve injury (PNI) remains far from …

MSC-Derived exosomes suppress colorectal cancer cell proliferation and metastasis via miR-100/mTOR/miR-143 pathway

B Jahangiri, M Khalaj-Kondori, E Asadollahi… - International Journal of …, 2022 - Elsevier
Exosomes derived from mesenchymal stem cells (MSCs) are mostly responsible for the
therapeutic effects of MSCs. To show the therapeutic effects of the human bone marrow …

[HTML][HTML] Extracellular vesicles as an emerging drug delivery system for cancer treatment: Current strategies and recent advances

Z Wang, H Mo, Z He, A Chen, P Cheng - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Cancer is one of the primary causes of death worldwide, and its morbidity and mortality rates
are increasing rapidly. However, standard treatment modalities (surgery, radiotherapy …

Simvastatin increases temozolomide‐induced cell death by targeting the fusion of autophagosomes and lysosomes

S Shojaei, N Koleini, E Samiei, M Aghaei… - The FEBS …, 2020 - Wiley Online Library
Temozolomide (TMZ) is a chemotherapy agent used to treat Grade IV astrocytoma, also
known as glioblastoma (GBM). TMZ treatment causes DNA damage that results in tumor cell …

Intranasal delivery of mesenchymal stem cells-derived extracellular vesicles for the treatment of neurological diseases

S Herman, I Fishel, D Offen - Stem Cells, 2021 - academic.oup.com
Neurological disorders are diseases of the central nervous system (CNS), characterized by
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …

Potential role of exosomes in cancer metastasis

W Tian, S Liu, B Li - BioMed research international, 2019 - Wiley Online Library
High cancer mortality is attributed to metastasis to a large extent. However, cancer
metastasis remains devoid of dynamic monitoring and early prevention in terms of current …