Fundus-controlled perimetry (FCP, also called 'microperimetry') allows for spatially-resolved
mapping of visual sensitivity and measurement of fixation stability, both in clinical practice as …

With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Endpoint development trials are underway across the spectrum of retinal disease. New
validated endpoints are urgently required for the assessment of emerging gene therapies …

Stargardt macular dystrophy (Stargardt disease; STGD1; OMIM 248200) is the most
prevalent inherited macular dystrophy. STGD1 is an autosomal recessive disorder caused …

Inherited retinal dystrophies (IRDs) are bilateral genetic conditions of the retina, leading to
irreversible vision loss. This study included 55 eyes afflicted with IRDs affecting the macula …

Importance Functional end points for clinical trials investigating the efficacy of emerging
treatments for Stargardt disease type 1 (STGD1) are needed. Objective To assess the yearly …

Retinal microperimetry (MP) is a procedure that assesses the retinal sensitivity while the
fundus is directly observed, and an eye tracker system is active to compensate for …

PURPOSE To systematically assess the ability to detect change and retest reliability for a
panel of visual function assessments in ABCA4 retinopathy. DESIGN Prospective natural …

The aim of this review article is to describe the specific features of Stargardt disease and
ABCA4 retinopathies (ABCA4R) using multimodal imaging and functional testing and to …

Inherited retinal dystrophies (IRDs) are genetic disorders that lead to the bilateral
degeneration of the retina, causing irreversible vision loss. These conditions often manifest …