Bacterial Zinc Metalloenzyme Inhibitors: Recent Advances and Future Perspectives

R Di Leo, D Cuffaro, A Rossello, E Nuti - Molecules, 2023 - mdpi.com
Human deaths caused by Gram-negative bacteria keep rising due to the multidrug
resistance (MDR) phenomenon. Therefore, it is a priority to develop novel antibiotics with …

Zinc binding and chelating compounds as inhibitors of bacterial metalloproteases and human matrix metalloproteases

FA Rahman - 2023 - munin.uit.no
Bacterial multi-drug resistance is a major health problem worldwide. Inhibition of bacterial
virulence is suggested to be a promising strategy in the development of new antibacterial …

基质金属蛋白酶抑制剂在糖尿病视网膜病变的研究进展

朱素华, 徐圣秋 - 临床荟萃, 2022 - huicui.hebmu.edu.cn
基质金属蛋白酶(matrix metalloproteinases, MMPs) 是一种能够降解几乎所有类型的细胞外
基质的酶, 在多种生理过程中发挥着重要作用, 同时受到多种机制调控, 包括天然的金属蛋白酶 …

Bacterial zinc proteases

C Capasso, CT Supuran - Metalloenzymes, 2024 - Elsevier
Metalloproteases present in various clostridial species (Clostridium tetani and Clostridium
botulinum) as well as in Bacillus anthracis are zinc proteases among the most …

Matrix metalloproteinase 8 as a marker and actor in cancer

K Juurikka - 2023 - oulurepo.oulu.fi
Cancer is a disease with a significant health impact: approximately 10 million cancer-related
deaths occur worldwide every year. Cancer research has unraveled the diverse nature …

Proline et prolinol: azacycles prototypiques pour le développement de peptidomimétiques et la synthèse d'agents médicinaux

JB Garsi - 2023 - papyrus.bib.umontreal.ca
La proline est un acide aminé unique qui se caractérise par un cycle pyrrolidine qui lui
confère des propriétés physiques et chimiques spécifiques comparé aux autres 20 acides …