Many aging adults experience some form of hearing problems that may arise from auditory
peripheral damage. However, it has been increasingly acknowledged that hearing loss is …

Presbycusis–age-related hearing loss–is a key communication disorder and chronic
medical condition of our aged population. The cochlear nucleus is the major site of …

Age-related changes within the auditory brainstem typically include alterations in inhibitory
neurotransmission and coding mediated by GABA and glycinergic circuits. As part of an …

Tone detection and temporal gap detection thresholds were determined in CBA/CaJ mice
using a Go/No-go procedure and the psychophysical method of constant stimuli. In the first …

Age-related hearing loss is a prominent deficit, afflicting approximately half of the geriatric
population. In many cases, the person may have no deficits in detecting sounds, but …

Temporal envelope processing is critical for speech comprehension, which is known to be
affected by normal aging. Whereas the macaque is an excellent animal model for human …

Age-related hearing loss, presbycusis, can be thought of, in part, as a slow progressive
peripheral deafferentation. Previous studies suggest that certain deficits seen in presbycusis …

Recently, we characterized the more severe nature of hearing loss in aged Type 2 diabetic
human subjects [Frisina, ST, Mapes, F., Kim, S., Frisina, DR, Frisina, RD, 2006 …

Low‐level lead (Pb) exposure is a risk factor for learning disabilities, attention deficit
hyperactivity disorder (ADHD), and other neurological dysfunction. It is not known how Pb …

Neurons in the superior paraolivary nucleus (SPON) of the rat respond to the offset of pure
tones with a brief burst of spikes. Medial nucleus of the trapezoid body (MNTB) neurons …