Glutamatergic and GABAergic neurons in pontine central gray mediate opposing valence-specific behaviors through a global network
Extracting the valence of environmental cues is critical for animals' survival. How valence in
sensory signals is encoded and transformed to produce distinct behavioral responses …
sensory signals is encoded and transformed to produce distinct behavioral responses …
Leveraging ultra-high field (7T) MRI in psychiatric research
Non-invasive brain imaging has played a critical role in establishing our understanding of
the neural properties that contribute to the emergence of psychiatric disorders. However …
the neural properties that contribute to the emergence of psychiatric disorders. However …
Uncovering hemispheric asymmetry and directed oscillatory brain-heart interplay in anxiety processing: an fMRI study
A Ghouse, G Pfurtscheller, G Schwarz… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
Brain-heart interactions (BHI) are critical for generating and processing emotions, including
anxiety. Understanding specific neural correlates would be instrumental for greater …
anxiety. Understanding specific neural correlates would be instrumental for greater …
High throughput mRNA sequencing reveals potential therapeutic targets of Si-Ni-San in the pons for a stress-induced depression model
J Li, Y Zhang, T Li, B Nie, F Qi, Q Chen… - Frontiers in …, 2024 - frontiersin.org
Background An accumulating body of research indicates that the pons is related to the
occurrence of depression. Si-Ni-San (SNS) is a well-known Chinese herbal formula that is …
occurrence of depression. Si-Ni-San (SNS) is a well-known Chinese herbal formula that is …
Safety of BI 1358894 in patients with major depressive disorder: Results and learnings from a phase II randomized decentralized clinical trial
C Reist, P Li, T Le Nguyen… - Clinical and …, 2024 - Wiley Online Library
The feasibility of conducting a fully remote, interventional, phase II decentralized clinical trial
(DCT) was investigated in major depressive disorder (MDD). Key learnings were collated to …
(DCT) was investigated in major depressive disorder (MDD). Key learnings were collated to …
[HTML][HTML] Restoration of C-type natriuretic peptide and glial fibrillary acidic protein expression in fear centers and intrinsic cardiac ganglia by theta frequency sound …
Background C-type natriuretic peptide (CNP) can be altered during stress and has protective
effects in both the heart and brain; the functions of both organs can be positively affected by …
effects in both the heart and brain; the functions of both organs can be positively affected by …
Abnormal resting-state functional connectivity in subregions of amygdala in adults and adolescents with major depressive disorder
L Guan, R Liu, C Wang, Q Fan, J Zhou, Y Wang… - BMC psychiatry, 2024 - Springer
Background The different symptoms of major depressive disorder (MDD) in adolescents
compared to adults suggested there may be differences in the pathophysiology between …
compared to adults suggested there may be differences in the pathophysiology between …
f-MRI and High Throughput mRNA sequencing reveals potenti-al therapeutic targets of Si-Ni-San in a stress-induced depressionmodel
J Li, Y Zhang, T Li, F Qi, Q Chen, T Chen, Y Liu, Y Li… - 2023 - researchsquare.com
Background: Despite the confirmed good efficacy of Si-Ni-San (SNS) in the treatment of
depression, its antidepressant mechanism has remained unclear. Th-is study aimed to …
depression, its antidepressant mechanism has remained unclear. Th-is study aimed to …