We provide an overview of imaging, histopathology, genetics, and multidisciplinary
treatment of giant cell tumor of bone (GCTB), an intermediate, locally aggressive but rarely …

Sarcomas comprise a heterogeneous group of mesenchymal neoplasms. They can be
grouped into 2 general categories, soft tissue sarcoma and primary bone sarcoma, which …

Background Surgical resection with curative intent for giant cell tumor of bone (GCTB) may
be associated with severe morbidity. This interim analysis evaluated reduction in surgical …

Osteonecrosis of the jaw (ONJ) presents clinically as exposed, necrotic bone in the maxilla
or mandible of at least 8 weeks' duration, with or without the presence of pain, infection, or …

The giant cell tumour of bone (GCT) is a locally aggressive intraosseous neoplasm of
obscure biological behaviour. Although well defined in clinical, radiological and histological …

Wnt signaling increases bone mass by stimulating osteoblast lineage commitment and
expansion and forms the basis for novel anabolic therapeutic strategies being developed for …

Comprehending the pathogenesis of giant cell tumor of bone (GCT) is of critical importance
for developing novel targeted treatments for this locally-aggressive primary bone tumor. GCT …

Giant cell tumour of bone : Current Opinion in Oncology Giant cell tumour of bone : Current
Opinion in Oncology Log in or Register Subscribe to journalSubscribe Get new issue alertsGet …

Background Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive, rarely
metastazing bone tumor. This is a retrospective study evaluating a large series of GCTB …

Giant cell tumour of bone (GCTB) is a benign osteolytic tumour with three main cellular
components: multinucleated osteoclast-like giant cells, mononuclear spindle-like stromal …