Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives
H Sun, Y Li, P Zhang, H Xing, S Zhao, Y Song… - Biomarker …, 2022 - Springer
Toll-like receptors (TLRs) are a large family of proteins that are expressed in immune cells
and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in …
and various tumor cells. TLR7/8 are located in the intracellular endosomes, participate in …
Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
Y Yang, H Li, C Fotopoulou, P Cunnea… - Frontiers in …, 2022 - frontiersin.org
Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …
TLR9: a friend or a foe
The innate immune system is a primary protective line in our body. It confers its protection
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …
through different pattern recognition receptors (PRRs), especially toll like receptors (TLRs) …
Exploring the prognostic implications of cuproptosis-associated alterations in clear cell renal cell carcinoma via in vitro experiments
Z Xing, L Cui, Y Feng, Y Yang, X He - Scientific Reports, 2024 - nature.com
This study investigated the impact of novel copper ionophores on the prognosis of clear cell
renal cell carcinoma (ccRCC) and the tumor microenvironment (TME). The differential …
renal cell carcinoma (ccRCC) and the tumor microenvironment (TME). The differential …
Molecular mechanisms of chloroquine and hydroxychloroquine used in cancer therapy
JB De Sanctis, J Charris, Z Blanco… - Anti-Cancer Agents …, 2023 - benthamdirect.com
Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …
in cancer therapy. A recent approach has been to scrutinise drugs used in the clinic for other …
Lysosome-related biomarkers in preeclampsia and cancers: Machine learning and bioinformatics analysis
H Tang, X Luo, X Shen, D Fan, J Rao, Y Wan… - Computers in Biology …, 2024 - Elsevier
Background Lysosomes serve as regulatory hubs, and play a pivotal role in human
diseases. However, the precise functions and mechanisms of action of lysosome-related …
diseases. However, the precise functions and mechanisms of action of lysosome-related …
The OSR9 Regimen: A New Augmentation Strategy for Osteosarcoma Treatment Using Nine Older Drugs from General Medicine to Inhibit Growth Drive
RE Kast - International Journal of Molecular Sciences, 2023 - mdpi.com
As things stand in 2023, metastatic osteosarcoma commonly results in death. There has
been little treatment progress in recent decades. To redress the poor prognosis of metastatic …
been little treatment progress in recent decades. To redress the poor prognosis of metastatic …
[PDF][PDF] The Prognostic Potential of Cuproptosis and Cuproptosis-Related Alteration of Clear Cell Renal Cell Carcinoma
Z Xing, L Cui, Y Feng, Y Yang, X He - 2022 - scholar.archive.org
The Prognostic Potential of Cuproptosis and Cuproptosis-Related Alteration of Clear Cell
Renal Cell Carcinoma Page 1 Page 1/17 The Prognostic Potential of Cuproptosis and …
Renal Cell Carcinoma Page 1 Page 1/17 The Prognostic Potential of Cuproptosis and …
Potential Value of the Stretched Exponential and Fractional Order Calculus Model in Discriminating Between Hepatocellular Carcinoma and Intrahepatic …
J Xie, C Li, Y Chen, H Zhang, H Lin, G Yang, L Long - 2024 - benthamdirect.com
Background: In clinical practice, Preoperative differentiation between hepatocellular
carcinoma and intrahepatic cholangiocarcinoma is challenging but critical for treatment …
carcinoma and intrahepatic cholangiocarcinoma is challenging but critical for treatment …