Hydromorphone Prescription for Pain in Children—What Place in Clinical Practice?

F Rodieux, A Ivanyuk, M Besson, J Desmeules… - Frontiers in …, 2022 - frontiersin.org
While morphine is the gold standard treatment for severe nociceptive pain in children,
hydromorphone is increasingly prescribed in this population. This review aims to assess …

Simulation with Monte Carlo methods to focus quality improvement efforts on interventions with the greatest potential for reducing PACU length of stay: a cross …

JH Jones, N Fleming - BMJ open quality, 2024 - bmjopenquality.bmj.com
Background Time and money are limited resources to pursue quality improvement (QI)
goals. Computer simulation using Monte Carlo methods may help focus resources towards …

Morphine and hydromorphone pharmacokinetics in human volunteers: population-based modelling of interindividual and opioid-related variability

K Meissner, E Olofsen, A Dahan… - British Journal of …, 2024 - Elsevier
Background Morphine and hydromorphone have differing onsets, magnitudes, and
durations of effects and side-effects. Differences between opioids in their interindividual …

High bioavailability, short half-life, and metabolism into hydromorphone-3-glucuronide following single intramuscular and intravenous administration of …

M Sosa-Higareda, DSM Guzman… - American Journal of …, 2023 - Am Vet Med Assoc
OBJECTIVE To determine the pharmacokinetic parameters of hydromorphone hydrochloride
and its metabolite, hydromorphone-3-glucuronide (H3G), after a single IV and IM dose in …